This review briefly summarizes the current progress in cellular response to DSB.
本文将简单概述当前对DSB细胞应答系统的研究进展。
Understanding cellular response to environmental stress has broad implications for human disease.
细胞对环境应激的反应与人类疾病有广泛的联系。
Similarly, the cellular response to the environmental mutagens is not always initiated by DNA damage.
同样地,环境诱变剂诱发的细胞应答反应也不只是单纯地由DNA损伤所触发的。
Now there are two ways in endotoxin induced cellular response: the indirect way of cytokines and the direct way.
目前认为内毒素介导细胞的反应通过两个途径:细胞因子的间接作用及对细胞的直接作用。
Novel IFN receptor 1 binding proteins, DNA encoding them, and method of modulating cellular response to interferons.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
Novel IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations.
p53肿瘤抑制蛋白在细胞响应DNA损伤和其它基因组异常的过程中发挥重要作用。
In particular, the researchers found that two key genes were affected in the cellular response to decreased glucose consumption.
特别是,研究人员发现,葡萄糖消耗下降会影响细胞的两个关键基因。
Objective to explore the cellular response of human senescent diploid fibroblasts (2bs) to the DNA damage caused by methyl methanesulfonate (MMS).
目的观察衰老的人胚肺二倍体成纤维细胞(2bs)对烷化剂甲磺酸甲酯(MMS)诱导的DNA损伤的应答。
What has been discovered is that a single hormone molecule or neurotransmitter or a single photon of electromagnetic energy can trigger a cellular response.
已发现什么是单个分子或激素神经递质或单光子电磁能量可以引发细胞反应。
On a molecular level, this means that the apoptotic and autophagic response machineries share common pathways that either link or polarize the cellular responses.
在分子水平上,这意味着在细胞凋亡和自噬的反应机制有着共同的通道,要么链接或者要么分化某些细胞反应。
An important part of the cellular response to DNA damage is checkpoint activation - checkpoint kinases CHK1 and CHK2 phosphorylate key proteins to elicit cell-cycle blocks.
细胞对DNA损伤作出应答的一个重要过程是检查点活化(检查点激酶CHK1和CHK2使关键蛋白磷酸化,从而阻止正常的细胞周期。)
The contents mainly include mechanical stimulation signal, cells feeling the mechanical stimulation signal, force transduction mechanisms and cellular response to mechanical stimulation.
研究内容主要有力学刺激信号、细胞对力学刺激信号的感受及转导机制和细胞受力后的反应三部分内容。
Therefore, the aim of this study was to focus on the cellular response and events of dermal contraction and epidermal re-epithelialization during wound healing under the influence of AgNPs;
因此,本研究的目的是纳米银粒子存在情况下创面愈合时真皮收缩和表皮再生过程中细胞的应答和变化。
Paraspeckles are dynamic structures that are altered in response to changes in cellular metabolic activity.
旁斑是响应细胞代谢活性变化而改变的动态结构。
He mentioned immune response, cellular breakdown and glucose metabolism as immediate areas of research focus, and in his own laboratory plans to study rapamycin's effects on stem cells.
他提到免疫反应、细胞分解与糖代谢是当前的研究热点区域,他自己的实验室计划研究雷帕霉素对干细胞的作用。
In response to such incoming information, receptors on a cell's surface send signals to the nucleus that tweak gene expression and control cellular function.
细胞表面的受体对外界信息的相应反应就是将信息以信号的形式传递给启动基因表达和控制细胞功能的细胞核。
In response to the accumulation of misfolded proteins, the cellular alarm systems are switched on and stress responses are activated.
当细胞积累了大量的错误折叠蛋白后,细胞的报警系统被打开,细胞应激应答被激活。
We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.
筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。
Objective: to investigate specific cellular immune response to the HPV16E7 prophylactic vaccine in mice.
目的:探讨重组HPV16E7质粒免疫小鼠后诱导的细胞免疫反应。
Most existing vaccines elicit a targeted antibody response, but safely activating cellular immunity against many infectious diseases remains a challenging task.
多数现存疫苗所引发的是特定抗体反应,至于想要安全活化细胞免疫,来对抗许多传染病,目前还是一项挑战。
The research of overloading on cellular level may elucidate the mechanical effect on the formation, regeneration and growth of bone and the mechanism of cell response in bone.
细胞水平过载的研究可使人们进一步搞清应力对骨形成、重建和生长的影响及骨内细胞响应机制。
The hope is that these HI genes will produce a cellular immune response to HI and cause the body to make killer cells that are programmed to recognize and destroy cells that are infected with HI.
希望这种HI基因会产生针对HI病毒的细胞免疫反应,使机体产生杀伤细胞,程序化识别并毁被HI病毒感染的细胞。
CONCLUSION: Cellular immune response in the skin of the mice immunized with UV-attenuated cercariae might play an important role in the protective immunity against challenge infection.
结论:提示皮肤组织的细胞免疫反应在血吸虫减毒尾蚴免疫的宿主抗攻击感染保护性免疫中起重要作用。
Studies conducted in recent years found that response to radiation therapy in various cancers is better when certain types of cellular growth factors are blocked at the same time.
近年来实施的研究发现在放疗的同事一定种类的细胞因子被阻滞,各种癌症对放疗的反应要更好。
Immunological memory is an important characteristic of adaptive immune response and elucidation of its cellular basis is critical for vaccine exploration and disease prevention.
免疫记忆是适应性免疫应答的重要特征,其细胞学基础的阐明是疫苗开发和疾病预防的关键。
In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.
为了应对DNA损伤,细胞有一套复杂的机制,包括细胞周期停滞,诱导转录和DNA修复被激活。
Deacetylation of p53 occurs through interaction with the SIRT1 protein, a deacetylase that may be involved in cellular aging and the DNA damage response (19).
SIRT1蛋白,一种涉及到细胞衰老和DNA损伤反应的去乙酰基酶能够与p53结合,促使后者的去乙酰化(19)。
Adaptive response can be induced by low concentration of FA on MRC-5 cells and cellular adaptation is a complex process involving in a modulation of diverse cellular functions.
低剂量甲醛可诱导MRC - 5细胞适应性反应,多种蛋白参与细胞的适应性反应调控。
Adaptive response can be induced by low concentration of FA on MRC-5 cells and cellular adaptation is a complex process involving in a modulation of diverse cellular functions.
低剂量甲醛可诱导MRC - 5细胞适应性反应,多种蛋白参与细胞的适应性反应调控。
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