Objective The current study was designed to establish a new method for the analysis of cell cycle specific apoptosis.
目的建立一种新的细胞周期特异性凋亡检测方法。
Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.
细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶(CDK)复合物来调控。
Results Post-sorting confocal (PSC) method could exactly distinguish apoptotic and non-apoptotic cells in the specific cell cycle phases at the same time.
结果①流式细胞术分选后共聚焦显微镜分析技术(PSC)能同时、准确地鉴别不同细胞周期时相的凋亡细胞和非凋亡细胞。
In fact, as a specific molecular chaperone, HSP90 proteins are possibly involved in many important physiological processes such as signal transduction, cell cycle regulation and hormone response.
事实证明,作为一种特异的分子伴侣,HSP90除在细胞正常生长和应急保护中具有重要生理功能外,还与信号传导、细胞周期调控、激素应答等细胞内重要生理过程有关。
CONCLUSIONS:Panshengan is a cell cycle-specific drug which can arrest the cells at G1/G0 phase.
结论:盼生安是周期特异性药物,通过将细胞阻滞于G1/G0 期而抑制其增殖。
Conclusion: Preoperative short term (5-7 days) use PN can increase the cell proliferation, but it will do favor for using cell-cycle specific chemotherapy.
结论术前短期肠外营养(5 ~7天)可能会刺激肿瘤的生长增殖,但亦可能有利于发挥周期特异性化疗药物的疗效。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
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