Objective: To establish the method of microbial limit for Compound Cefalexin Capsules.
目的:建立头孢氨苄甲氧苄啶胶囊的微生物检查方法。
Objective To prepare lincomycin hydrochloride, cefalexin capsules and establish its standard for quality control.
目的研制以盐酸林可霉素、头孢氨苄为主药的胶囊剂。
Similarity factor was used to evaluate the effect of all those influencing factors on release profiles of cefalexin.
方法采用单因素试验对可能影响体外释放的各因素进行考察,用相似因子法对释放曲线进行比较。
Result: Through the reaction of 7-ADCA and Dane Salt, one step crystallization gives Cefalexin with the total yield 89.4% .
结果:7- 氨基-3-去乙酰氧基头孢烷酸(7-ADCA)和苯甘氨酸邓钠盐反应,只需要一步结晶即可得头孢氨苄,总收率89.4%。
Conclusion: the synthesis of Cefalexin by one step crystallization can greatly shorten the craft and lower the production cost.
结论:一步结晶法合成头孢氨苄可以大大缩短工艺过程,降低生产成本。
Objectives: It is more accurate and rational that the dissolution of Cefalexin tablets is determined by the self reference method.
前言:目的:使自身对照法测定头孢氨苄片溶出度的方法更加合理准确。
In this paper, the authors Adopt UV spectrophotometry to determine the content of. cefalexin and compare with the sutra iodimetry.
本文采用紫外分光光度法测定头孢氨苄的含量,并对其测定条件进行了研究。
Thermogravimetry was used to study the non-isothermal decomposition kinetics and the difference of stability between cefalexin and its excipients.
采用热重法研究头孢氨苄热分解非等温动力学和头孢氨苄与其制剂的稳定性差异。
OBJECTIVE Near infrared diffuse reflectance spectrophotometry (NIRDRS) and chemometrics were applied to the quantitative analysis of cefalexin in capsules.
目的:应用近红外漫反射技术和化学计量学的方法对头孢氨苄胶囊进行定量分析。
Method: The release processes of Cefalexin Tablets were determined simultaneously with FODT-601 Fiber-optic Medicine Dissolution Process Real Time Test System.
方法:用光纤溶出度实时测定仪,以对照品法实时监测头孢氨苄片的溶出过程。
According to the drug sensitive test, Gbacillus was most sensitive to imipenem but its drug resistance to penicillin, cidomycin, cefalexin, clindamycin ect was more than 50%.
药敏分析发现G菌对亚胺培南最为敏感,而对青霉素、庆大霉素、头孢氨苄、克林霉素等的耐药率均超过50%。
According to the drug sensitive test, Gbacillus was most sensitive to imipenem but its drug resistance to penicillin, cidomycin, cefalexin, clindamycin ect was more than 50%.
药敏分析发现G菌对亚胺培南最为敏感,而对青霉素、庆大霉素、头孢氨苄、克林霉素等的耐药率均超过50%。
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