Conclusion CDK4 expression may have prognostic significance in OSCC.
结论CDK4在OSCC内的表达可能具有预后意义。
ConclusionThe change of CDK4 expression may have prognostic significance in OSCC.
结论CDK4在OSCC中的表达变化可能具有预后意义。
CDK4 amplification could be correlated with HBV DNA integration and the progression of HCC.
CDK4的扩增可能与HBV -DNA的整合以及肝癌的进展有关。
AIM To analyze the expression and significance of cyclin dependent kinase 4 (CDK4) in chondrosarcoma of the jaws.
目的分析细胞周期素依赖激酶4 (CDK4)在颌骨软骨肉瘤的表达及意义。
ObjectiveTo investigate the change of CDK4 expression in oral squamous cell carcinoma (OSCC) and its prognostic significance.
目的探讨CDK4在口腔鳞状细胞癌(OSCC)中的表达变化与预后的关系。
ResultsDecrease of CDK4 LI significantly correlated with favorable survival outcome in the cases with surgery alone (P<0.005).
结果在单纯手术组，CDK4LI的降低与良好的预后生存显著相关（P<0.005）。
There was significant difference in the expression of TEP1 and CDK4 proteins between superficial and invasive stages (P< 0.05).
不同临床分期间TEP1和CDK4表达的差异均具有显著性意义（P<0.05）；
Objective to discuss the expression of CDK4 gene in astrocytoma, and the relationship between it and pathological classification.
目的探讨脑星形细胞瘤中cd K 4基因蛋白的表达，及其与星形细胞瘤病理学分级关系。
Conclusion CDK4 protein overexpression may play an important role in the development of BTCC. CDK4 may be a novel prognostic factor in BTCC.
结论：CDK4的过度表达可能在BTCC的进展中发挥了重要作用，CDK4可成为一种新的预后判断的参考指标。
Objective: to determine the expression of CDK4 and P16 and its relation to the clinicopathological characteristics in some epidermal tumors.
目的：探讨CDK4、P 16在某些表皮肿瘤中的表达及其与临床病理特征的关系。
Objective Antisense CDK4 was transfected into human colorectal cancer cells HT29 to examine the effect of it on the growth and proliferation of HT29 cells.
目的将反义CDK4导入人结肠癌细胞株ht29细胞，观察其对肿瘤细胞生长的影响。
Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
Labeling index (li) was presented by the percentage of positive cells, and change of CDK4 li between biopsy and surgical operations was examined for association with survival.
标记指数(LI)为阳性细胞率，检测了活检与外科手术之间CDK4 LI变化与生存之间的关系。
The active complex of cyclin D/CDK4 targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression (3).
活跃的cyclinD/CDK4复合体靶向视网膜母细胞瘤蛋白以利于磷酸化，促进可以激活G1/S期基因表达的转录因子E2F的释放（3）。
The active complex of cyclin D/CDK4 targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression (3).
活跃的cyclinD/CDK4复合体靶向视网膜母细胞瘤蛋白以利于磷酸化，促进可以激活G1/S期基因表达的转录因子E2F的释放（3）。
应用推荐