Thus, gene transfer of CD40L has been proposed as an efficient means to treat malignancies.
这样，通过转导CD 40 L基因有可能成为治疗恶性肿瘤的一种有效的方法。
Results: M231 and ECV cell line and fresh clinic breast cancer cell are highly expressed CD40 but no CD40L.
结果：CD 40高表达于乳腺癌细胞株m231、乳腺癌新鲜标本及血管内皮细胞，上述3种细胞基本不表达CD 40l。
Conclusion the soluble human CD40L truncate expressed in prokaryotic cells showed inhibiting effect on the growth of tumor cells.
结论原核表达的截断型人可溶性CD 4 0 L具有抑制肿瘤细胞生长作用。
Recent studies have confirmed that both CD40 molecule and its ligand CD40L played important roles in various stages of atherosclerosis.
近年来研究证实CD40分子与其配体CD40L在动脉粥样硬化的各个阶段均起重要作用。
Conclusion: Patients with ACS show significantly increased coexpression of CD40 system and circadian variation at CD40L concentration on platelets.
结论急性冠脉综合征患者血小板表达的CD 40及CD 40 L显著增高，且血小板表达的CD 40l呈现出昼夜节律的变化规律。
Objective to investigate the role of CD40 and CD40 ligand (CD40L) in the pathogenesis of systemic lupus erythematosus (SLE) and its clinical significance.
目的探讨CD 40及其配体(CD40L)在系统性红斑狼疮(SLE)发病机制中的作用及临床意义。
Compared to placebo group, simvastatin can inhibit the vascular intima proliferation the expression of PAPP-A and CD40L were also decreased significantly.
与安慰剂组比较，辛伐他汀组内膜增生减少，而管腔面积的减少减轻，与之相对应的是PAPP - A的表达及血管组织CD 40l蛋白含量也明显降低。
Objective To investigate the expression of platelet-derived CD40 ligand(CD40L), P-selectin(CD62P) in peripheral blood and its clinical significance in asthma.
目的探讨血小板源性CD40配体（CD40L）、血小板P选择素（CD62P）在哮喘患者外周血中的表达及其临床意义。
Conclusion Simvastatin and rosiglitazone can decrease serum level of lipids and exert anti-atherosclerotic effect by reducing the expression of CD40 and CD40L.
结论辛伐他汀与罗格列酮均能降低血脂，并通过降低巨噬细胞CD 40和CD 40l表达发挥抗动脉粥样硬化作用。
Objective To investigate potential mechanisms by which CD40 CD40 ligand (CD40L) interaction may be involved in the pathogenesis of lupus glomerulonephritis (LN).
目的探讨CD40 CD 40配体(CD40L)相互作用在狼疮肾炎(LN)发病机制中的可能作用。
Conclusions: the enhanced level of serum soluble CD40L might be a reliable prognostic indicator for ACS and might be as a marker of the activity of the coronary lesion.
结论：血清可溶性CD 40 L升高是判断acs的可靠血清学指标，且可能是冠脉病变的活动性标志物。
CD40L may participate in thrombosis and activation of platelet. The soluble CD40L levels increase persistently in patients with acute cerebral infarction and acute coronary syndrome.
CD 40 L可能参与血栓形成和血小板活化，急性脑梗死和急性冠状动脉综合征患者血液中的可溶性CD 40 L持续性增高。
But it is short of further exploration in the correlation between matrix metalloproteinase and CD40L or risk stratification and predicting the value of heart incidence in unstable angina.
但在不稳定性心绞痛患者中，基质金属蛋白酶的水平与CD 40l的相关性以及与不稳定性心绞痛患者的危险度分层、发生心脏事件的预测价值方面尚缺乏进一步的探索。
Methods ADSC was isolated from fat tissue by liposuction and culture expanded. Cells at passage2 were observed for the expression of HLA, HLA, B7-1, B7-2, CD40 and CD40L by FACs analysis.
方法体外培养人脂肪抽吸术中获取的脂肪干细胞，体外培养至第二代，流式细胞仪检测免疫分子HLA、HLA、B7-1、B7-2、CD40的表达。
Objective to explore the relationship between platelets activation and CD40L expression, and to determine whether these biochemical processes of platelets can be influenced by aspirin and heparin.
目的探讨血小板活化与表达CD 40l的关系以及阿司匹林、肝素对此过程的影响。
In KD patients, CD40L expression on CD4 + T-cells and E-selection was correlated with the occurrence of coronary artery lesions but not CD40L expression on CD8 + T-cells and not soluble CD40L levels.
细胞表面CD 40l表达及e -选择素与川崎病冠状动脉损伤有关，而CD 8 +T细胞表面CD 40l的表达及可溶性CD 40l与冠状动脉损伤无明显相关性。
In KD patients, CD40L expression on CD4 + T-cells and E-selection was correlated with the occurrence of coronary artery lesions but not CD40L expression on CD8 + T-cells and not soluble CD40L levels.
细胞表面CD 40l表达及e -选择素与川崎病冠状动脉损伤有关，而CD 8 +T细胞表面CD 40l的表达及可溶性CD 40l与冠状动脉损伤无明显相关性。
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