PTH and CBZ are potent inducers of hepatic enzyme and can lower the serum concentration of VPA.
丙戊酸钠和卡马西平是强有力的肝酶诱导剂,使丙戊酸钠血浓度降低。
CONCLUSIONS: The finger prick blood can be used for TDM of CBZ by HPLC instead of venous blood.
结论:应用HPLC法对卡马西平进行TDM,可以用手指血代替静脉血。
Conclusion: Fukang tablet has protective effects on the cerebella synapse injury induced by CBZ.
结论:中药复康片对CBZ所致大鼠小脑突触损伤有预防保护作用。
Aim: To establish the model of rat bone marrow inhibition induced by carbamazepine tablets (CBZ).
目的:建立卡马西平(CBZ)诱导的骨髓抑制大鼠模型。
AIM To investigate the pharmacokinetic profile of carbamazepine (CBZ) in Chinese epilepsy patients.
目的考察中国癫痫患者卡马西平的群体药动学参数。
Aim: to study the preventive effect of Fukang tablet on liver toxicity induced by carbamazepine (CBZ).
目的:研究复康片预防卡马西平(CBZ)肝毒性的效果。
Conclusion FT can prevent or antagonize the inhibition of hematopoiesis of rat bone marrow induced by CBZ.
结论复康片可预防或拮抗卡马西平对大鼠骨髓造血功能的抑制。
Objective: To study the effect of long-term administration of CBZ on the structure and function of rats' cerebellum.
目的:研究长期服用卡马西平对大鼠小脑结构及功能的影响。
Objective The purpose of this study was to evaluate clinical practicality of carbamazepine (CBZ) made in our country in treatment of manic episode.
目的评价国产卡马西平(CBZ)在治疗躁狂发作中的临床实用性。
Conclusions It is feasible that saliva can replace serum to monitor CBZ concentration that is stable in saliva for the guidance of clinical medication.
结论血中CBZ的浓度与唾液中的浓度呈高度相关,且稳定性好,可以用唾液代替血液监测CBZ浓度来指导用药;
Objective Explore the possibility of finger-prick blood being monitored for therapeutic drug monitoring (TDM) of carbamazepine (CBZ) instead of venous blood.
目的探讨利用手指血取样代替静脉血对卡马西平进行TDM(治疗药物监测)的可能性。
Objective To observe the different prevention effect of TCM on the damnification of cerebellum induced by Carmaciping (CBZ) if Fukang tablets were given in different time.
目的观察中药复康片不同时间给药对卡马西平所致大鼠小脑毒性的影响。
Objective To establish reversed phase HPLC method for simultaneous determination of the concentration of carbamazepine(CBZ)and diltiazem(DZ) in serum, using diazepam as internal standard.
目的建立反相高效液相色谱(HPLC)法,以安定为内标,同时测定血清中卡马西平(CBZ)和地尔硫(DZ)的浓度。
Objective: Antiepileptic drugs (AEDS) may affect serum thyroid hormone concentration. this study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), or valproate (VPA) for epilepsy.
目的抗癫痫药物可以引起甲状腺激素水平改变,本研究旨在探讨抗癫痫药卡马西平(CBZ)、丙戊酸钠(VPA)对男性癫痫病人甲状腺激素水平的影响。
Objective: Antiepileptic drugs (AEDS) may affect serum thyroid hormone concentration. this study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), or valproate (VPA) for epilepsy.
目的抗癫痫药物可以引起甲状腺激素水平改变,本研究旨在探讨抗癫痫药卡马西平(CBZ)、丙戊酸钠(VPA)对男性癫痫病人甲状腺激素水平的影响。
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