Therefore, derivatives of camptothecin are becoming the focus of research.
因而喜树碱衍生物成为研究的热点。
Camptothecin and its derivatives are alkaloids possessing anti tumor activities.
喜树碱及其衍生物是一类具有抗癌活性的生物碱。
No available rules can explain changes of 10-oh camptothecin content under all treatments.
各处理对喜树幼苗内10 -羟基喜树碱含量的影响无规律可循。
Objective: to explore the effect of hydroxy camptothecin on colorectal carcinoma cells in vitro.
目的探讨羟基喜树碱对肠癌细胞的体外作用。
Camptothecin was coupled with 2-furonic acid, pyridinecarboxylic acid, niacin and isonicotinic acid through ester bond.
喜树碱与呋喃甲酸、吡啶甲酸、烟酸和异烟酸通过酯键进行偶联。
Objective:To investigate drug-resistance mechanism of the camptothecin(HCPT)-resistant stomach cancer cell line SGC-7901/HCPT.
目的：探讨人胃癌耐羟基喜树碱细胞株即SGC-7901/HCPT的耐药机制。
Results Suspension culture cells grew well in MS medium and cell homogeneity and camptothecin content were superior to those in other media.
结果悬浮培养细胞在M S培养基中细胞生长良好，细胞分散性和喜树碱积累优于在其他培养基中。
Objective to investigate the effects of camptothecin (CPT 11) plus 5 FU in treating patients with 5 FU resistant advanced colorectal cancer.
目的观察开普拓(CPT11)联合5 -氟尿嘧啶(5FU)治疗5FU耐药晚期大肠癌的效果。
Result the problems of camptothecin such as solubility, stability and side effects could be solved by special delivery methods and strategies.
结果通过一些特殊的传递方法与策略，可以解决喜树碱类药物所存在的溶解度、稳定性、毒性和不良反应等问题。
Tryptophan synthase (TSB) and tryptophan decarboxylase (TDC) are two key enzymes in camptothecin biosynthesis as they link primary and secondary metabolism.
色氨酸合成酶(TSB)和色氨酸脱羧酶(TDC)是喜树碱合成过程中连接初生代谢和次生代谢过程的两个关键酶。
Results demonstrated that taxol, harringtonine, homoharringtonine and camptothecin exhibited significant inhibition of cell growth of B16BL6 and HT1080 cells.
结果表明紫杉醇、三尖杉酯碱、高三尖杉酯碱及喜树碱对B16BL6和HT1080细胞增殖均有很强的抑制作用。
Through reviewing the process of developing camptothecin and its derivatives, to discuss its philosophy meanings and the value to development of other plant drugs.
通过对喜树碱类药物研发过程的历史回顾，探讨其存在的哲学意义和对其它植物药研发的价值。
Tryptophan synthase (TSB) and tryptophan decarboxylase (TDC) are two key enzymes in camptothecin biosynthetic pathway as they links primary and secondary metabolism.
色氨酸合成酶(TSB)和色氨酸脱羧酶(TDC)是喜树碱合成过程中连接初生代谢和次生代谢过程的两个关键酶。
This invention provides a new camptothecin derivative with anti-tumor activity and structure as the right formula dissolving in water, its application, and its drug combinations.
本发明提供一类具有以右式结构式所示结构的新的具有抗肿瘤活性的能溶于水的喜树碱衍生物及其应用、以及包括该化合物的药物组合物。
Methods: After incubated with BHRF1 antisense oligonucleotide, BHRF1 CNE2 cells were treated with camptothecin, and tested for the alterations of proliferative ability and apoptotic index.
方法：检测反义阻断BHRF1表达后BHRF 1 -CNE2细胞在喜树碱作用下增殖能力和凋亡指数的变化。
Interaction between trypsin and CamptothecinThe interaction of trypsin with camptothecin (CPT) in vitro was studied by ultraviolet (UV) absorption spectral and fluorescence spectral methods.
通过紫外光谱和荧光光谱的方法研究了喜树碱与胰蛋白酶的体外相互作用。
In the symbiosis system imposed by the exogenous Camptothecin, both the fluorescence of microtubules in plant and fungi were stronger than normal, maybe there were new microtubule synthesized.
外源喜树碱处理的菌根共生体系中，植物与真菌的微管的荧光强度明显增强，可能表明了新微管的合成。
In the symbiosis system imposed by the exogenous Camptothecin, both the fluorescence of microtubules in plant and fungi were stronger than normal, maybe there were new microtubule synthesized.
外源喜树碱处理的菌根共生体系中，植物与真菌的微管的荧光强度明显增强，可能表明了新微管的合成。
应用推荐