This specificity of the binding pocket is half polar and half neutral according to the surface charge property.
依照表面电荷性质,这个结合袋的特异性是半极性半中性的。
The mutations, including in-frame deletions at exon 19 and substitutions at exon 18 or exon 21, cluster around ATP-binding pocket of TK domain.
这些突变均发生在酪氨酸激酶域的ATP结合域附近,突变为19号外显子上的缺失突变,或18和21号外显子上的替代突变。
Moreover, the substituents on the bicyclic chromophore can also produce strong van der Waals and hydrophobic interactions with the residues located at the exterior part of the binding pocket.
同时,抑制剂双环上的取代基团也能和活性口袋外部的部分残基形成一定的范德华和疏水相互作用。
The conserved surface patch and the deep pocket are responsible for binding to PP2A and ATP, respectively.
这种保守的表面补丁和深口袋负责分别与PP2A和ATP结合。
The conserved surface patch and the deep pocket are responsible for binding to PP2A and ATP, respectively.
这种保守的表面补丁和深口袋负责分别与PP2A和ATP结合。
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