• In the study that led to the FDA approval, most patients were refectory to bendamustine and rituximab.

    在向FDA申报批准的临床研究中,大部分病人都对苯达莫司汀和利妥昔单抗耐药。

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  • As a new generation of anti-cancer drugs, bendamustine has an obvious effect on a wide range of cancers.

    盐酸苯达莫司汀作为新一代抗癌药物,对多种癌症具有明显的治疗作用。

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  • Toxic epidermal necrolysis has been reported for rituximab, but the relationship of toxic epidermal necrolysis to bendamustine has not been determined.

    已报道有关利妥昔单抗的毒性表皮坏死,但毒性表皮坏死和苯达莫司汀的关系尚不确定。

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  • Other malignant neoplasms were added to warnings and precautions, noting reports of premalignant and malignant diseases that developed in patients treated with bendamustine.

    其它恶性的肿瘤被加到警告和注意事项中。苯达莫司汀治疗的病人中有恶性肿瘤和恶性肿瘤前的的报道。

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  • In late February 2016, the FDA approved the anti-CD20 agent obinutuzumab(Gazyva) in combination with bendamustine for patients with follicular lymphoma following rituximab-based therapy.

    2016年2月底,FDA批准了对接受过利妥昔单抗治疗的滤泡性淋巴瘤患者使用抗CD20单抗obinutuzumab和苯达莫司汀联合的方案。

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  • In late February 2016, the FDA approved the anti-CD20 agent obinutuzumab(Gazyva) in combination with bendamustine for patients with follicular lymphoma following rituximab-based therapy.

    2016年2月底,FDA批准了对接受过利妥昔单抗治疗的滤泡性淋巴瘤患者使用抗CD20单抗obinutuzumab和苯达莫司汀联合的方案。

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