• Bcl-2 protein is a new target of anticancer drugs with bright prospect now.

    2蛋白目前肿瘤药物研究很具前景靶点

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  • Objective To study the effect of BCL-2 gene on skin carcinogensis due to arseniasis caused by coal-burning.

    目的研究BCL - 2基因燃煤型砷中毒皮肤恶性病变过程中的作用。

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  • Objective To study the effect of curcumin on apopsis and bcl-2 expression in SW480 human colon cancer cells.

    目的探讨姜黄素结肠癌细胞株SW480诱导凋亡影响及其作用机制。

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  • We used immunohistochemistry to detect the gastric mucosal cells apoptosis, proliferation and the expression of BCL-2, BAX.

    免疫组化方法检测黏膜细胞凋亡增殖以及凋亡相关基因BCL-2BAX表达

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  • Bcl-2 expression score showed that a strong positive expression happened in LN group but a weak expression in the control group.

    免疫组化评分显示层粘连蛋白有强阳性表达,正常对照组阳性表达;

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  • The expressions of protooncogenes bcl-2 - cmyc and P53 play a important role in regulating the apoptosis of SMC in the As plaques.

    提示这些基因表达动脉粥样硬化斑块组织中的平滑肌细胞凋亡重要调节作用

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  • CLL cells are strongly dependent on a survival molecule called Bcl-2, which switches off self-destruct signals in the cancer cells.

    慢性淋巴细胞性白血病细胞依赖生存分子Bcl - 2分子可以关闭了癌症细胞的凋亡信号

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  • To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.

    研究Bcl - 2反义寡核苷酸联合照射肺癌细胞的抑制作用。

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  • The cortex's immunohistochemistry expression of Bcl-2 was no obvious change(P>0.05). The expression of Caspase-3 decreased obviously(P<0.05).

    PNS治疗组大鼠脑皮质Bcl-2表达阳性细胞数量明显变化P>0.05),Caspase-3表达的阳性细胞数量明显下降(P<0.05)。

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  • This paper studied the effect of moderate exercise on peripheral blood lymphocytes apoptosis and Bax, Bcl-2 Gene expression of mental stress rats.

    研究中等负荷运动训练心理应激大鼠淋巴细胞凋亡及其调控基因影响

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  • Results: With the time prolongation, the expression of BCL-2 protein (BI) dropped progressively, AST level markedly enhanced and apoptosis cell appeared.

    结果随着缺血时间延长BCL - 2蛋白表达指数呈进行性降低AST值则逐渐升高,凋亡细胞出现

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  • AIM: to investigate the effects of renal ischemic preconditioning (RIP) on immature myocardial cell apoptosis and expressions of Bcl-2, Bax and Fas proteins.

    目的探讨缺血预处理(rip)未成熟心肌细胞凋亡相关蛋白表达影响

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  • The DNA contents of spleen and bursa, the ratio of apoptosis and the expression of caspase-3 and Bcl-2 in the spleen and bursa were measured by flow cytometry.

    流式细胞仪检测应激后不同时间脾脏法氏细胞DNA含量细胞凋亡以及Caspase - 3和Bcl - 2表达

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  • In the workers, a strong expression of Bcl-2-like was shown in secondary spermatocytes, and a lower expression level in spermatogonia and primary spermatocytes.

    工蚁次级母细胞最高,精原细胞初级精母细胞中低。

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  • It is concluded that the apoptosis of spleen and bursa cells was obviously affected by heat stress and regulated by the expression of caspase-3 and Bcl-2 protein.

    据此说明高温应激明显影响脾脏法氏囊细胞凋亡这种细胞凋亡变化受Caspase - 3Bcl - 2表达调节

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  • Objective to investigate the relationship and disciplinarian between apoptosis and expressions of Bcl-2 and Bax protein after intracerebral hemorrhage (ICH) in rats.

    目的研究鼠脑出血(ICH)血肿周围细胞凋亡及其凋亡相关蛋白bcl - 2Bax表达变化规律关系

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  • Objective: to investigate the bcl-2 and bax protein expression and its association with apoptosis and cell proliferation in Helicobacter pylori (HP) related gastritis.

    目的探讨幽门螺杆菌hp引起胃粘膜上皮细胞凋亡增殖改变HP致癌作用的可能机制。

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  • Translocation of Nur77 from the nucleus to the mitochondria can regulate its association with Bcl-2 and control the release of cytochrome c, thereby triggering apoptosis (12,13).

    Nur77细胞核易位线粒体可以调节Bcl-2联合控制细胞色素c释放从而引发细胞凋亡12,13)。

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  • Results Compared with the control groups, insulin can significantly increased the expression of FOS and BCL-2 protein both in the ischemic cerebral cortex and in basal ganglia (P<0.001).

    结果与假手术对照组未用药相比胰岛素显著上调缺血大脑皮层基底节区FOSBCL - 2蛋白表达( P<0 .0 0 1)。

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  • It's expected that ABT-737 and similar drugs that prompt cancer cells to die will be relatively non-toxic to most healthy cells, because healthy cells don't rely so heavily on Bcl-2 to stay alive.

    促进癌细胞死亡ABT- 737同类的药物认为大多数健康细胞相对无毒的,因为健康细胞不用很多地依赖Bcl - 2生存

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  • Conclusion PKC took place translocation activation during cerebral ischemia reperfusion, PKC promoted the expression of FOS and BCL 2. Their complex role influenced the neuronal apoptosis.

    结论缺血再灌注期间PKC发生易位激活PK C促进FOSBCL - 2表达几个因素综合作用影响神经细胞凋亡。

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  • Objective to study the relationship between apoptosis and rejection, expression of BCL 2 and UCHL1.

    目的探讨细胞凋亡排斥反应BCL2UCHL1表达之间关系

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  • Objective to explore the effects of CCK on BCL - 2 - associated apoptotic pathways in cholangiocarcinoma.

    目的探讨胆囊收缩素(CCK)胆管癌细胞凋亡的调节作用及机制。

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  • Objective To investigate the effect of Ginsenoside (GS) on apoptosis and expression of bcl 2 and bax genes in kidney after high energy shock wave (HESW).

    目的探讨人参总皂甙对高能冲击波细胞凋亡相关基因影响

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  • Objective To investigate the effect of Ginsenoside (GS) on apoptosis and expression of bcl 2 and bax genes in kidney after high energy shock wave (HESW).

    目的探讨人参总皂甙对高能冲击波细胞凋亡相关基因影响

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