Conclusions Sulfide can significantly reduce the proliferation of ECV304, change the cell cycle distribution and arrest cells in G2-M phase where apoptosis may be induced.
结论舒林酸的硫化代谢产物能够显著抑制血管内皮细胞的增殖活性,改变细胞的周期分布,使细胞阻滞于G 2期,并可能在此期诱导其凋亡。
They feared that if the UK cell learned of Rauf's arrest they would believe their capture was imminent and either lash out or try to go to ground.
他们担心,如果在英国的团伙得知劳夫被捕的消息,他们会认为自己即将被捕,因而,要么发起攻击,要么转入地下。
A grisly cell phone photograph distributed by the news agency Agence France Presse appeared to show the arrest of a bloodied Gadhafi.
法新社发布了一张恐怖的照片,这张手机拍摄的照片似乎记录的正是浑身是血的卡扎菲被捕时候的情景。
This hyperacetylation causes cell cycle arrest and cell death in cancer cells but not in normal cells.
这种高乙酰化导致了癌症细胞的细胞周期阻止和细胞死亡,而正常细胞中没有出现。
Conclusion: chalcone can inhibit the growth of BGC823 and arrest the cell cycle.
结论:查尔酮可以抑制BGC823细胞生长,并呈剂量-反应关系。
Instead the cells underwent cell cycle arrest with features of senescence.
代之以衰老为特征的细胞周期阻滞的表现。
In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.
为了应对DNA损伤,细胞有一套复杂的机制,包括细胞周期停滞,诱导转录和DNA修复被激活。
CONCLUSIONS:Panshengan is a cell cycle-specific drug which can arrest the cells at G1/G0 phase.
结论:盼生安是周期特异性药物,通过将细胞阻滞于G1/G0 期而抑制其增殖。
The mechanism of causing the inhibition of allogeneic CD4+T cell proliferation is "tryptophan hunger" and "toxic effects of tryptophan metabolites", it cause cell growth arrest or apoptosis.
其造成CD4+T细胞增殖抑制的机制为“色氨酸饥饿”和“色氨酸代谢产物毒性作用”造成细胞生长停滞甚至凋亡。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.
结论:向胃癌细胞中导入外源性FHIT基因可以抑制肿瘤细胞增殖,诱导细胞凋亡并引起细胞生长周期阻滞。
Objective To study whether tamoxifen(TAM) can induce growth arrest and apoptosis of ER-negative MA782 mouse breast cancer cell line and to explore the molecular mechanisms.
目的探讨三苯氧胺(TAM)治疗乳腺癌分子作用机制及其与细胞周期的关系。
Once the TP53 protein is activated, it can trigger the expression of several genes that influence cell cycle arrest and DNA repair or lead to apoptosis when DNA repair is failed.
一旦TP53蛋白被激活就能引发数种基因的表达来影响细胞周期阻滞、DNA修复、或者在DNA修复失败后引导凋亡发生。
It induces cell cycle arrest in late G1 phase and may induce bone morphogenic protein-2 (BMP-2).
它诱导细胞周期停滞在G1期晚期,可能诱导成骨蛋白2 (BMP - 2)。
Result Cancer cell growth arrest in S phrase reducing by somatostatin was detected, which resulted in reverting its chemotherapy resistance to DOX (P<0.05).
结果生长抑素诱导胆囊癌细胞生长停滞于细胞周期的S期,能明显降低癌细胞对DOX的耐药性(P<0 .0 5 ) ;
Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro (2, 3).
p53的激活能够引起细胞周期捕获和DNA修复或细胞凋亡(1)。离体或者在体情况下,p 53可以在多个位点被几个蛋白激酶进行磷酸化(2,3)。
Researchers believe that the combination therapy may activate an enzyme that controls cancer cell proliferation and induce cell cycle arrest ultimately causing the interruption of cancer growth.
研究人员相信这种联合疗法能够激活抑制癌细胞生长的酶,诱导最终抑制癌细胞生长的细胞周期停滞。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
Experimental studies have proved that it has cytotoxic effect on leukemia cells and to induce programed cell death without arrest of bone marrow by regulating immune.
实验研究证明六神丸对白血病有细胞毒作用,并能诱导凋亡,同时能调节免疫功能,不抑制骨髓。
We used human acute promyelocytic leukemia cell line HL-60 to study the anti-tumor mechanisms of lycorine in two aspects: apoptosis and cell cycle arrest.
我们以人急性早幼粒白血病细胞株HL-60作为实验对象进行石蒜碱抗白血病作用机制研究,在凋亡相关基因表达变化和细胞周期阻滞两方面展开探讨。
Like other DNA damage agents, LDM induces cell cycle arrest, apoptosis and mitotic cell death.
作为DNA损伤剂,LDM可以诱导细胞周期阻滞、凋亡和裂亡。
Like other DNA damage agents, LDM induces cell cycle arrest, apoptosis and mitotic cell death.
作为DNA损伤剂,LDM可以诱导细胞周期阻滞、凋亡和裂亡。
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