The other (complementary or antisense) strand always has a sequence that matches the first strand, with each C complemented by a G, and each A by a T, and vice versa.
另一条链（互补链或反义链）的序列总是与第一条链相匹配，即C与G，A与T，反过来也一样。
With the rapid development of genetic engineering and metabolic regulation, antisense technology displays its fascination to the world as a mild regulation genetic tool.
随着基因工程技术的蓬勃发展和代谢调控研究的深入，反义技术作为一种温和调控的基因工程技术，开始向世人展示其无穷的魅力。
As a new territory of genetic pharmacology, antisense nucleic acid drug has been promoting the development of tumor research as well as the study of genetic and infectious diseases.
反义核酸药物是基因药理学的一个新领域，对于肿瘤、遗传病以及传染病的防治具有重要意义。
Cationic liposome can enhance AS ODN antisense inhibitory effect.
阳离子脂质体能促进AS - ODN的反义抑制作用。
Recent advances in development and application of antisense drugs were reviewed.
本文综述了近期反义药物开发与应用的进展。
Then, the content of melanin in antisense TRP-1 transfected melanocyte was detected.
测定TRP - 1反义核酸转染黑素细胞后细胞内黑素含量的变化。
Phase II trials with an antisense oligonucleotide against HSP-27 in CRPC are underway.
以HSP-27为靶点的反义寡核甘酸正处于第二期临床试验中。
A strategy of shotgun antisense gene silencing was used to generate a rice mutant library.
尝试利用鸟枪反义基因沉默策略构建水稻突变体库。
Finally, its antisense imaging was accomplished in the breast cancer-bearing nude mouse models.
最后在荷乳腺癌裸鼠模型中进行反义显像。
Results PCNA antisense oligodeoxynucleotides could significantly inhibit the growth of BT325 cells line.
结果PCNA反义寡核苷酸可明显抑制BT325细胞的生长；
Objective To examine the influence of antisense MCP-1 on MCP-1 production and mesangial cell proliferation.
目的研究反义单核细胞趋化蛋白1 (MCP - 1)对系膜细胞MCP - 1分泌及增生的影响。
Objective: to screen the high performance, specific and nontoxic anti HBV antisense oligonucleotide fragment.
目的：筛选出高效特异而无毒的抗hbv反义寡核苷酸片段。
Objective To study inhibition of VEGF expression in human bladder carcinoma cells by antisense oligonucleotides.
目的观察vegf反义寡核苷酸对膀胱癌细胞VEGF表达的抑制情况。
CONCLUSION: EAAC1 antisense oligonucleotide has the neuroprotective effect against acute cerebral ischemia injury.
结论：EAAC 1反义寡核苷酸对急性脑缺血损伤有神经保护作用。
Objective to observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
目的观察结缔组织生长因子(CTGF)反义rna对实验性肝纤维化的影响。
He tested the hypothesis by giving mice an antisense, which is a molecular compound that blocked the production of LRP.
他给小鼠服用反意物质—一种阻碍LRP表达的分子化合物—用来验证自己的猜想。
The aim of gene therapy is to transfect DNA into target cells, in which utilizing antisense oligonucleotides is a main method.
基因治疗是将DNA转染进入目的细胞，修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。
DAPI staining was used to investigate the role of HPK1 antisense oligodeoxynucleotides in hippocampus neuron death induced by OGD.
采用DAPI染色技术观察hpk1反义寡核苷酸对OGD诱导的海马神经元凋亡的作用。
Objective To study the reverse effect on the malignant phenotype of human NPC cells CNE2 transfected with EBV-LMP1 antisense gene.
目的研究EB病毒LMP1反义基因对人鼻咽癌CNE2细胞恶性表型的逆转作用。
Objective: To study the antisense oligonucleotide mediated inhibition on telomerase activity and cell proliferation of GBC-SD cell.
目的：探讨反义寡核苷酸对胆囊癌细胞端粒酶活性的影响及对胆囊癌细胞生长增殖的作用。
Objective To explore the efficiency of transfection of antisense oligonucleotides HA-2741 by ultrasound mediated liposome microbubbles.
目的探讨超声介导脂质体微气泡转染反义寡核苷酸ha- 2741的有效性。
Objective To evaluate the therapeutic effect of antisense oligonucleotide targeting Survivin in the treatment of tumor-bearing nude mice.
目的评价生存素反义寡核苷酸在荷肝癌小鼠中的治疗作用。
Objective to construct eukaryotic expression vector of antisense MBD1 gene fragment and to provide a tool for studying MBD1 gene function.
目的构建反义MBD1基因片段真核表达载体，为研究MBD1基因功能提供工具。
Objective: to study the effect of VEGF antisense RNA on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的：研究血管内皮生长因子(VEGF)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
Results: After the transfection, antisense RNA had been successfully expressed respectively, and NK cells activity had been improved about 15%.
结果：转染后反义rna均得到高水平表达，并使NK细胞的杀伤活性提高约15%。
Objective To explore the effects of antisense proliferating cell nuclear antigen (PCNA) gene on proliferation activities of bladder cancer cells.
目的探讨反义增殖细胞核抗原(pcna)基因对膀胱癌细胞增殖活性的影响。
Objective To study the effects of antisense oligodeoxynucleotide(AS/TF) for rat tissue factor (TF) on the myocardial ischemic reperfusion injury.
目的：研究组织因子（TF）反义寡脱氧核苷酸（AS/TF）对大鼠心肌缺血再灌注损伤的作用。
Objective To study the effects of antisense oligodeoxynucleotide(AS/TF) for rat tissue factor (TF) on the myocardial ischemic reperfusion injury.
目的：研究组织因子（TF）反义寡脱氧核苷酸（AS/TF）对大鼠心肌缺血再灌注损伤的作用。
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