The versatile compound is endostatin, a human protein that inhibits angiogenesis, the growth of new blood vessels in the body.
这种多功能化合物是内皮抑制素,一种抑制血管生成,即身体内新血管生长的人体蛋白质。
Although this process is a normal part of the body's ability to grow and heal itself, angiogenesis is also the path through which tumors transition from benign to malignant.
这个过程是一个身体增长和愈合能力正常功能的一部分,而肿瘤从良性向恶性转变也是通过血管生成。
Two angiogenesis inhibitors have been developed that have a broad spectrum of anticancer activity, yet virtually no side effects.
目前,已有两种具有广谱抗肿瘤活性且无明显副作用的血管生成抑制剂面世。
Recently, many endogenous angiogenesis inhibitors have been discovered, some of them are currently in various stages of clinical trials.
近年来,研究发现了多种内源性血管生成抑制因子,其中一些已进入了临床试验阶段。
Recently, it was found that chemokines and their receptors were involved in proliferation, angiogenesis and metastasis of various types of cancer cells.
近年来研究发现,趋化激素与其受体在癌细胞的增生、血管新生与转移上扮演重要的角色。
OBJECTIVE To study the effects of artesunate on angiogenesis.
目的观察青蒿琥酯对新生血管生成的影响。
The concept of therapeutic angiogenesis is defined in recent years.
治疗性血管生成是近年来提出的新概念。
Endogenous angiogenesis inhibitors act as tumor suppressor proteins.
内源性血管生成抑制剂可作为一种抑癌蛋白。
By targeting the proteins that lead to angiogenesis, tumor growth can be halted.
以引起血管形成的蛋白作为靶向,肿瘤的生长可以停止下来。
Components of vascular basement membrane are involved in regulating angiogenesis.
血管基膜的成分参与调节血管的新生。
Tumor associated angiogenesis plays a pivotal role in the growth and metastasis of tumors.
肿瘤血管生成在肿瘤的生长和转移中起着重要的作用。
Glycans regulate tumour proliferation, invasion, haematogenous metastasis and angiogenesis.
聚糖能调节肿瘤增殖、侵袭、转移和血管生成。
The molecular mechanisms behind the inhibition of angiogenesis have not yet been elucidated.
但其确切的抗血管形成的作用机制尚未阐明。
Oncogenic mutations initiate tumorigenesis but angiogenesis is necessary for expansion of tumor mass.
癌基因突变引起肿瘤形成,而血管生成则是肿瘤扩大所必需的。
Purpose To study the angiogenesis induced by OS 732 cell line and its inhibition by anti VEGF antibody.
目的:研究人骨肉瘤OS 732细胞系促血管生成作用及血管内皮生长因子(VEGF)抗体对其血管生成的抑制作用。
Expression of CD24 and its relationship with angiogenesis and tumor cell proliferation in colorectal carcinoma.
大肠癌CD24的表达及其与肿瘤细胞增殖和血管形成的关系。
Objective: To explore the relationships between COX - 2 expression and angiogenesis in oral malignant melanoma.
目的探讨环氧化酶-2(COX-2)表达和口腔恶性黑色素瘤血管生成的关系。
Objective To explore the relationship between COX-2 expression and angiogenesis in salivary gland adenocarcinoma.
目的探讨环氧合酶- 2 (COX - 2)表达和涎腺腺癌血管生成的关系。
Conclusion CTPD not only has direct inhibition function on tumor cells but also has inhibition function on angiogenesis.
结论桂枝茯苓汤不仅对肿瘤细胞有直接的抑制作用,还具有抑制血管生成的作用。
VEGF121 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability (1).
VEGF121参与到了血管再生、血管内皮细胞生存、生长、迁移和血管渗透(1)。
Objective To investigate the role of angiogenesis in acute and chronic leukemia and its correlation with clinical condition.
目的探讨急慢性白血病患者骨髓血管新生情况与临床病情的关系。
To investigate the correlation between the dynamic MRI enhancement characteristics and tumor angiogenesis in gastric carcinoma.
探讨胃癌动态增强MRI强化表现与肿瘤血管生成的关系。
The researchers looked for other proteins involved in angiogenesis and ultimately discovered MIC-1 as a regulator of this process.
研究人员找寻涉及血管形成的其他蛋白并且最终发现MIC - 1是血管形成这一过程的调控者。
Objective: to investigate the expression of trefoil factor 1 (TFF-1) and its relationship with the angiogenesis in gastric cancer.
目的:研究三叶肽因子1 (TFF - 1)在人胃癌组织中的表达及其与胃癌血管形成的关系。
The relative biological features as angiogenesis, apoptosis, hypoxic and proliferation can be reflected by PET early and correctly.
PET可以早期准确地反映肿瘤相关生物特征,如血管生成、凋亡、乏氧和增殖等。
And the genes involved in the regulation of tumor angiogenesis play an increasingly important role in the field of tumor researches.
与肿瘤血管生成相关的调控基因的研究也越来越受到重视。
In addition, several angiogenesis inhibitors have been approved by the FDA as therapy for cancer or intraocular neovascular disorders.
此外,一些血管生成抑制剂已被FDA批准作为治疗癌症或眼内新生血管性疾病。
Objective To investigate the correlation between the dynamic MRI enhancement characteristics and tumor angiogenesis in gastric carcinoma.
目的探讨胃癌动态增强MRI强化表现与肿瘤血管形成的关系。
Objective: To explore the role of vascular endothelial cells and fibroblasts derived from tumors in the tumor angiogenesis in solid tumors.
目的:探讨肿瘤血管内皮细胞和成纤维细胞在肿瘤血管形成中的作用。
Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis.
肿瘤血管生成是肿瘤生长转移的关键步骤,是促血管生成因子和抑制因子作用失衡的结果。
应用推荐