They alter the way it cleaves amyloid precursor protein.
它们改变了这个酶切割淀粉样蛋白前体的方式。
The severity of amyloidosis depends on which organs the amyloid deposits affect.
淀粉样变的严重性依赖于淀粉样蛋白沉积在哪个器官。
The sample is then examined under a microscope in a laboratory to check for signs of amyloid.
这个样本会送往实验室在显微镜下检查是否有淀粉样蛋白沉积。
LEHRER: Your book talks about a new technique that allows doctors to image amyloid plaques in the brain.
LEHRER：你的书介绍了一种新技术，医生可以成像脑中的淀粉样蛋白斑块。
“In my view, the sweet spot for amyloid-lowering trials is mild Alzheimer’s disease, ” Dr. Selkoe said.
Selkoe还说：“在我看来，轻度老年痴呆症患者是降低淀粉样蛋白试验的最佳对象。”
The history of the study of amyloid is studded with illustrious names.
淀粉样蛋白的研究历史布满了辉煌的名字。
The amyloid which occurs in certain endocrine glands is designated AE protein.
出现在内分泌腺上的淀粉样蛋白是特定的AE蛋白。
The amount of these amyloid plaques in the brain is used as a measurement of the severity of Alzheimer's.
脑中淀粉样白斑量的多少可以作为衡量阿尔茨海默病严重程度的指标。
The CR1 gene is involved in protecting the brain by clearing out amyloid plaques that can build up in Alzheimer's patients.
CR 1基因通过清除会在老年痴呆症患者大脑中沉积的类淀粉斑，也具有保护大脑的功能。
Three weeks of chronic sleep deprivation was enough to accelerate the deposition of amyloid plaque in the brains of the mice.
慢性剥夺老鼠的睡眠达三周就足以使老鼠脑中淀粉样蛋白斑（amyloidplaque）的含量加速累积。
Amyloid beta itself might be injuring nerve cells or the plaques, made of accumulations of amyloid beta, could be the culprits.
淀粉样β蛋白本身可能损伤神经细胞或者有它聚集形成的老年斑才是罪魁祸首。
Using sophisticated scanning techniques, her team has located DNA of this herpes virus specifically within the amyloid plaques in the brain.
使用复杂的扫描技术，她的团队已经在脑中的淀粉样蛋白斑块中特异性的定位了这种疱疹病毒的DNA。
The drug, called PMX205, prevented inflamed immune cells from gathering in brain regions with Alzheimer's lesions called amyloid plaques.
被称作PMX205的这种药物，可阻止炎症免疫细胞在大脑中阿尔茨海墨症病变区（即淀粉样蛋白斑）聚集。
There is reason not to accept other forms of proof, like scans or cerebrospinal fluid that show changes in amyloid in the brain, the F.D.A. says.
FDA说有理由不接受其他形式的证明，如扫描结果或显示脑部淀粉样蛋白变化的脑脊液。
One of the products, with the long-winded name amyloid beta-peptide 42, has the unfortunate property that its molecules like to stick to each other.
所形成的产物之一有一个冗长的名字——淀粉样贝塔-肽42，它具有一种不祥的特性，即它们分子彼此之间容易纠缠在一起。
That's because amyloid, although important, is just one of the many toxic proteins that swell the neurons when the lysosomal system breaks down.
这是因为，尽管该蛋白很重要，但也只是在溶酶体系统崩溃之后，众多浸润神经细胞的毒性蛋白的其中一种。
Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
当一种叫淀粉样前体蛋白（APP）的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
This symposium deals with renal disease but it is appropriate to begin with a brief review of our present understanding of the nature of amyloid.
这篇综述是关于肾脏疾病的，但是不妨简单回顾一下我们目前对淀粉样蛋白的本质的了解。
The gene is also involved in removing clumps of rogue protein known as amyloid plaques, which are commonly seen in the brains of Alzheimer's patients.
该基因还参与消除常见于老年痴呆症大脑中称为类淀粉斑(amyloid plaques)的恶性淀粉蛋白凝块。
Electron microscopy reveals the characteristic fibrils of amyloid and in early cases this technique is occasionally essential for the diagnosis to be made.
电子显微镜能显示出淀粉样蛋白纤维的特征，在早期的病例中这项技术有时是诊断所必需的。
It contains antibodies against a protein called beta-amyloid, which many Alzheimer's researchers believe plays a pivotal role in the progression of the disease.
它包含能够对抗一种淀粉样蛋白(beta -amyloid)的抗体，许多阿滋海默症研究者都认为这种淀粉样蛋白在疾病的形成中扮演了关键的角色。
For the past decade there has been a lot of work on drugs called secretase inhibitors, which alter the activity of the enzymes that create amyloid beta-peptide 42.
在过去的10年里人们对被称为分泌酶抑制剂的药物进行了大量研究，这种药物可以改变酶类产生淀粉样贝塔-肽42的活动。
Results from a new laboratory study, published earlier this month, suggest it may also slow the formation of the amyloid plaques associated with Alzheimer's disease.
本月初公布的一项新的实验室研究结果表明，它可能还能减缓与老年痴呆症相关的淀粉斑的形成。
He added that there was a 37% reduction in serum amyloid - a marker of inflammation in mice - suggesting that vegetable consumption may inhibit inflammatory activity.
他还补充到，老鼠身上炎症状态的标志——血清淀粉减少了37%，暗示食用蔬菜可抑制炎症活性。
Earlier work done by her team has shown that, in mice at least, the herpes infection of nerve cells induces accumulation of beta amyloid, the main component of amyloid plaques.
她的团队已经在早期做了大量的工作，至少在小鼠中，疱疹病毒感染的神经细胞导致了beta-淀粉的沉积，而这是淀粉样蛋白斑块的主要成分。
Traditional drug development in Alzheimer's disease is taking too narrow an approach by focusing intensively on the buildup of amyloid beta-protein in the brain, Dr. Nixon says.
传统的治疗老年痴呆症的药物研发思路仅仅集中在淀粉样β蛋白的累积上，Nixon博士说。
In the examination of tissue for amyloid the most reliable technique is detection of the characteristic birefringence in polarised light exhibited by sections stained with Congo red or Sirius red.
在淀粉样蛋白的组织检查中最可靠的技术是刚果红或天狼星红染色切片在偏振光检查下出现特征性双折射。
In the examination of tissue for amyloid the most reliable technique is detection of the characteristic birefringence in polarised light exhibited by sections stained with Congo red or Sirius red.
在淀粉样蛋白的组织检查中最可靠的技术是刚果红或天狼星红染色切片在偏振光检查下出现特征性双折射。
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