AKT inhibitors have been used in trials on cancer patients before but with limited success.
AKT抑制剂以前在癌症患者身上做过实验，但效果有限。
"This underscores the importance of discovering the origin of active Akt in glioblastomas," he said.
“这突出了发现胶质母细胞瘤中活性Akt蛋白的重要性，”他说。
Decreased PTEN protein and increased AKT protein might be a marker for the early detection of the occurrence of colorectal cancer in patients with UC.
PTEN蛋白表达的明显降低和AKT蛋白表达的明显增强有可能成为早期监测uc癌变的一个辅助指标。
Conclusion: ROS, PTEN and p-AKT are involved in the signaling pathway of glucose-stimulated insulin secretion in INS-1cell, as signaling molecules in insulin secretion.
结论：ROS、PTEN及P -AKT参与了葡萄糖刺激INS - 1细胞分泌胰岛素的信号通路，成为介导胰岛素分泌的信号分子。
Zakrzewicz will present data from studies showing that the transcription factor Foxo-1, first described in 1999, can be inactivated by shear stress via Akt-mediated phosphorylation.
Zakrzewicz在他的综述中所提供的研究数据表明Foxo - 1转录因子(1999年首次被描述)可以被剪切应力通过Akt所介导的磷酸化作用所灭活。
The AKT-mediated signal pathway has been shown to be impaired in patients with schizophrenia, and antipsychotic medication may induce AKT activation, to compensate for the impairment.
AKT介导的信号通路在精神分裂症患者中发现有受损，而抗精神分裂症药物可以导致AKT激活，补偿这种受损。
We propose that the elevated levels of phosphorylated Akt may come from active forms of NK1R, and it's possible that a better response might be obtained by simultaneously blocking EGFR and NK1R.
我们预测高浓度的磷酸化akt蛋白可能来自活化的NK1R受体，所以同时抑制EGFR和NK1R受体可能获得更好的效果。
We propose that the elevated levels of phosphorylated Akt may come from active forms of NK1R, and it's possible that a better response might be obtained by simultaneously blocking EGFR and NK1R.
我们预测高浓度的磷酸化akt蛋白可能来自活化的NK1R受体，所以同时抑制EGFR和NK1R受体可能获得更好的效果。
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