• The key of antibody-mediated immunological therapy is strong specificity of target antigen, low immunogenicity, high affinity of antibody and so on.

    抗体介导免疫治疗关键抗原特异性,抗体的免疫原性亲和力高等

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  • Conclusion With the increase of the immunization times, the affinity of antibody come to mature and the proportion of dominant linear epitopes of BSA became higher.

    结论抗体抗原亲和力免疫次数增加趋向饱和,BSA的线性表位为优势表位,随免疫次数的增加比重逐渐增强。

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  • Because this method was to simulate the process of antibody maturation in vivo, the obtained antibodies was not only fully humanized but also with relatively high affinity.

    方法体外模拟抗体亲和力成熟过程,使得到抗体不但可以完全人源化而且可以具有较高的亲和力。

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  • Strategy was established for construction of repertoire antibody library with affinity chromatography purifying antigen, antigen immunizing human lymphocytes, RT-PCR and phage display technology.

    建立杂交瘤单抗亲和层析纯化抗原、抗原体外致敏淋巴细胞RT-PCR克隆人抗体基因噬菌体呈现技术构建人源抗体策略

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  • Conclusion Error-prone PCR is an effective and simple method for affinity maturation of antibodies isolated from a phage antibody library.

    结论错配pcr结合噬菌体展示技术提高单链抗体亲和力有效简便手段

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  • The residue activity of modified enzyme is 32.8% when the affinity to antibody disappear and the stability of modified enzyme is promoted obviously.

    得到修饰抗体结合能力消失,保留酶比活力32.8% ,酶的常温稳定性稳定性均有显著提高

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  • Typically, in previous reports, the purification of CP mainly relied on the antibody, liquid chromatography and affinity tag-based strategies.

    先前的研究中,CP分离主要依赖抗体液相色谱以及合标签纯化等技术。

    youdao

  • Typically, in previous reports, the purification of CP mainly relied on the antibody, liquid chromatography and affinity tag-based strategies.

    先前的研究中,CP分离主要依赖抗体液相色谱以及合标签纯化等技术。

    youdao

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