Active efflux mechanism exist not only in FQNS resistant strains, but also in FQNS susceptible strains.
主动外排机制不仅存在于FQNS耐药菌株，而且也存在于FQNS敏感菌株。
ABSTRACT Objective: To investigate active efflux of drugs in clinical isolated strains of Escherichia coli.
目的：研究临床分离的大肠杆菌多重耐药株和敏感株中抗菌药物的主动外排系统。
Reverse transcriptase-polymerase chain reaction (RT-PCR) was used to measure the mRNA levels of active efflux gene CDR1 and CDR2.
用逆转录-聚合酶链反应(RT - PCR)方法检测主动外排泵基因CDR1和CDR2的表达水平。
Conclusions Active export of norfloxacin or ciprofloxacin is prevalent in clinical isolates of Entrococci and efflux mechanism is a cause of clinically fluoroquinolone resistance in Entrococci.
结论诺氟沙星、环丙沙星的主动泵出机制普遍存在于临床分离肠球菌，并且是粪肠球菌对诺氟沙星、环丙沙星的耐药机制之一。
Conclusions Active export of norfloxacin or ciprofloxacin is prevalent in clinical isolates of Entrococci and efflux mechanism is a cause of clinically fluoroquinolone resistance in Entrococci.
结论诺氟沙星、环丙沙星的主动泵出机制普遍存在于临床分离肠球菌，并且是粪肠球菌对诺氟沙星、环丙沙星的耐药机制之一。
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