Objective To explore clinical arrhythmia feature and the change of endothelium function in aconitine poisoning.
目的探讨乌头碱中毒致心律失常的表现和对内皮功能的影响。
In addition, They also reduced the incidence of ventricular tachcardia and ventricular fibrillation induced by aconitine in …
降低结扎大鼠左冠状动脉前降支诱发心律失常的发生率。
Therefore, to culture toxic dosage-awareness and drug habit in patients is the key to prevent and reduce the rate of aconitine alkaloids poisoning.
因此培养患者有毒中药用药量、防中毒意识和改善产地用药习惯是从根本上预防和减少乌头类生物碱中毒的关键。
Pharmacological results showed that compounds 1, 5, 7, 8, 14, 15, 17 exhibited protective effects against experimental arrhythmias induced by aconitine.
药理试验结果表明，其中化合物1、5、7、8、14、15、17等均能对抗乌头碱引起的实验性心律失常，其中化合物14、15、17疗效显著。
Objiective:To research the mechanisms of the venenons constituent of the Aconitum—aconitine, mesaconitine, hypaconitine on the membrane receptor of myocardial cell.
目的：研究乌头类有毒中药毒性成分乌头碱、新乌头碱和次乌头碱对心肌细胞膜受体作用的机制。
In early work, through a large number of animal experiments and clinical observation showed that Shuanghuanglian treat aconitine poisoning have significantly effect.
在前期工作中，通过大量动物实验和临床治疗观察，结果显示双黄连治疗乌头碱中毒疗效显著。
Five groups of B-ring substituted flavone and flavanone-7-O-isopropanolamine derivatives were synthesized and tested on rats for the ventricular arrhythmia induced by aconitine.
合成了五组B环具不同取代基的黄酮和黄烷酮- 7 - o -异丙醇胺衍生物，并进行了对乌头碱诱发大鼠室性心律失常预防作用的药理试验。
Objective to examine the feasibility of regarding the hydrolyzate from aconitine, new aconitine, and hypaconitine to be the decoction of radix aconite and the quality control index.
目的考察用乌头碱水解物、新乌头碱水解物、次乌头碱水解物的含量作为附片水煎剂及附片质量控制指标的可行性。
Objective To analyze the clinical and electrocardiogram data of 54 cases of acute aconitine poisoning and to investigate the clinical characteristic and electrocardiogram manifestations.
目的分析54例急性乌头碱中毒病例的临床和心电图资料，探讨其临床特征和心电图表现。
RESULTS: a total of 653 aconitine induced ADR cases were found, involving mainly the nervous system and the cardiovascular system, with arrhythmias of different types as the main symptom.
结果含乌头碱类药物致不良反应共653例，主要涉及神经和心血管系统，主要表现为各种类型心律失常。
METHODS:Spectrophotometry of ion-couple extraction was employed and methodology was examined for preparing standard curve , added aconitine recovery, precision, exclusivity, and durability.
方法：采用离子对萃取—分光光度法测定，并对标准曲线制备、加样回收率试验、精密度试验、专属性试验、耐用性试验等项目进行了方法学考察。
The content of aconitine in the single decoction recipe and combined decoction recipe would decrease with a decrease of rhubarb dose and would be presented by liner correlation in two recipes.
单煎与混煎组方中乌头碱的含量均随着大黄剂量的增加而减少，两者均呈线性相关。
The optimized formulation of aconitine ethosome is high in encapsulation efficiency and good in stability, and the anti-inflammatory and analgesic activity of aconitine ethosome was significant.
以优化工艺制得的乌头碱醇质体包封率较高、稳定性好，且具有良好的抗炎镇痛作用。
Methods Effects of quinidine and verapamil on the alteration of action potential duration induced by aconitine were studied by use of the whole cell patch clamp techniques in rat ventricular myocytes.
方法应用全细胞膜片钳技术记录乌头碱对大鼠心肌细胞动作电位时程的作用，分别给予奎尼丁、维拉·帕米处理比较二者对动作电位时程的影响。
Methods Effects of quinidine and verapamil on the alteration of action potential duration induced by aconitine were studied by use of the whole cell patch clamp techniques in rat ventricular myocytes.
方法应用全细胞膜片钳技术记录乌头碱对大鼠心肌细胞动作电位时程的作用，分别给予奎尼丁、维拉·帕米处理比较二者对动作电位时程的影响。
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