• The acetylation imparts greater stability to the dimensions of the hardboard.

    乙酰化使硬质纤维板具较大的尺寸稳定性。

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  • In the reaction of acetylation and nitration 1, 2? Dichloroethane was used as solvent.

    在乙酰化、硝化反应中引入了1,2 -二氯乙烷溶剂。

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  • Selective acetylation of tri-O-acetyl-C-aryl-D-gluco-and galacto-pyranosides was reported.

    本文报道了葡萄糖和半乳糖碳苷的选择性乙酰化。

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  • Conclusion Acetylation may participate in the regulation of NOS1 promoter activity in neuronal cells.

    结论乙酰化参与调节神经细胞中NOS1基因启动子活性。

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  • Cabamazepine treatment could induce a higher acetylation level of HSP90 and destroy its chaperon function.

    卡马西平处理可以使HSP90乙酰化水平升高,并且破坏HSP90的分子伴侣功能。

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  • Here's a video that animates the acetylation of histone proteins in the regulation of gene expression in cancer cells.

    下面的视频是关于在癌症细胞里的常规基因表达是如何进行组蛋白乙酰化作用(acetylationofhistone)的。

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  • Fischer suggests that drugs that specifically enhance H4K12 acetylation, if they can be developed, might do the trick.

    Fischer倒认为,如果真有特异性增强H4K12乙酰化反应的药物被开发出来,也可能是骗人的。

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  • The level of his-tone acetylation is determined by the activities of histone acetyltransferases and histone deacetylases.

    组蛋白乙酰转移酶和组蛋白去乙酰酶活性共同决定了组蛋白的乙酰化水平。

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  • Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.

    组蛋白乙酰化促进基因表达,而去乙酰化则抑制基因表达。

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  • One challenge: acetylation has many roles in the body, so a drug would have to boost this process specifically in the brain.

    先别急,因为还有一个问题没有解决,那就是,乙酰在人的身体中发挥着许多作用,如果人为注射乙酰的话,怎么能够保证所注射的乙酰能一定会用于脑部记忆呢?

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  • Conclusion APP expression on SH-SY5Y cells may increase through up-regulation of histone acetylation through P38MAPK pathway.

    结论P 38 MAPK信号通路可能通过上调组蛋白乙酰化水平增加SH - SY5Y的APP蛋白表达。

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  • Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression.

    赖氨酸乙酰化是一种蛋白质可逆的翻译后修饰作用,在基因表达调控中起重要作用。

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  • Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.

    组蛋白乙酰化和去乙酰化可调节染色体的多种功能,例如基因表达和染色体分离等。

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  • It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.

    人们很早就注意到,真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。

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  • With in-depth study, we found that protein acetylation have great influence in the secretion of cytokines, generation of NO and so on.

    随着研究的深入,发现蛋白质乙酰化状态对细胞因子的分泌、NO的产生等方面均有较大的影响。

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  • As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.

    如同阿尔茨海默病鼠,增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。

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  • Tropisetron Hydrochloride was synthesized from 1Hindol-3-carboxylic acid by chloride acetylation and condensation with Tropic alcohol.

    以3-吲哚甲酸为起始原料,经氯化亚砜酰氯化、与托品醇缩合合成了托烷司琼盐酸盐。

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  • The copolymer after acetylation and phosphonylation can react with dibutyl amine to yield the corresponding dibutylamidophosphate resin.

    经乙酰化,膦化反应后的共聚体可以与二正丁胺作用制得膦酰胺树脂。

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  • The methods of the modification of phospholipids were summarized, such as hydroxylation, hydrogenation, hydrolyzation, acetylation, and so on.

    本文主要介绍了磷脂的化学改性方法,例如:羟基化、氢化、酶水解、酰化等。

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  • Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.

    组蛋白乙酰化和去乙酰化可以改变染色质的结构,参与基因的表达调控和重编程。

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  • Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.

    组蛋白乙酰化与基因转录等生物效应有密切的关系,组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。

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  • In additional experiments, the researchers injected a drug into the brains of older mice to counter the drop in acetyl tag attachment, or acetylation.

    在另一个实验中,研究人员给年老的老鼠脑部注入了一种药物来阻止它们脑部乙酰物质的流失,帮助它们的脑部产生乙酰作用,结果完全在研究人员预料之中,辅助记忆的基因发挥了作用,年老的老鼠也可以像幼鼠那样恢复对以前事情的记忆。

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  • The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.

    组蛋白乙酰化修饰与基因的表达调控相关,参与了各种肺部疾病的病变过程。

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  • Gene expression is often closely related to the different chemical modification ends of protein, acetylation is a kind of common form of modification.

    组蛋白尾端不同的化学修饰往往和基因的表达调控有着密切的关系,乙酰化就是常见的一种修饰形式。

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  • Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.

    乙酰化反应使组蛋白让DNA解螺旋,允许了基因的表达发生,因此抑制乙酰化反应将从总体上降低基因的表达。

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  • Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.

    其他的工作集中在组蛋白乙酰化,这种化学修饰可以使DNA从组蛋白缠绕中解离出来,产生基因活性。

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  • The genetic switch involves acetylation, the introduction of an acetyl group into a molecule at the DNA level of chromatin resulting in genetic transcription.

    基因“开关”涉及乙酰化作用,也就是将乙酰基群在染色质的DNA水平上引入到分子中,由此完成基因转录。

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  • Histone deacetylase inhibitors increase the acetylation level of histone as well as some non-histone proteins, and specifically modulate some gene expression.

    组蛋白去乙酰酶抑制剂可提高组蛋白的乙酰化水平,并对一些非组蛋白成分产生影响,从而调节某些特定基因的表达。

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  • Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.

    结合以上去乙酞化酶抑制剂的实验结果,我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。

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  • Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.

    结合以上去乙酞化酶抑制剂的实验结果,我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。

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