这些研究人员将肽(蛋白质片段)化合物作为研究重点,该化合物为多发性骨髓瘤细胞所独有,对于这种细胞的生存至关重要。
The researchers deployed a combination of peptides—small pieces of protein—that are known to be specific to multiple myeloma cells and are important for their survival.
MultipleMyeloma研究基金会资助了一家小型生物科技企业的研究,发现了一种很有前途的新药,能够治疗多发性骨髓瘤,一种骨头中原生质细胞的癌症。
Research funded by the multiple myeloma Re — search Foundation at a small biotech led to a promising new drug for multiple myeloma, a cancer of plasma cells in bones.
MultipleMyeloma研究基金会资助了一家小型生物科技企业的研究,发现了一种很有前途的新药,能够治疗多发性骨髓瘤,一种骨头中原生质细胞的癌症。
Research funded by the Multiple MyelomaRe--search Foundation at a small biotech led to a promising new drug formultiple myeloma, a cancer of plasma cells in bones.
低倍镜显示多发性骨髓瘤异常浆细胞弥漫浸润骨髓。
At low power, the abnormal plasma cells of multiple myeloma fill the marrow.
目的:探讨多发性骨髓瘤(MM)的主要临床特点以及骨髓细胞形态学在MM诊断中的作用。
Objective To investigate the clinical features in patients with multiple myeloma (MM) and the significance of bone marrow cell morphology in MM diagnosis.
“我们已经知道,在B细胞过度表达或突变的NIK和TRAF3分子是与人类多发性骨髓瘤相关,”麦凯教授说。
"We already know that the over-expression or mutation of molecules known as NIK and TRAF3 in B cells is associated with human multiple myeloma," said Professor Mackay.
诱导治疗清除骨髓转移之神经母细胞瘤者较不清除者预后好。
Patients whose neuroblastoma cells in bone marrow are cleared by induction therapy get better prognosis than those are not.
还有,当大多数人听到的诊断早幼粒细胞白血病,淋巴瘤或多发性骨髓瘤,他们的反应是惊愕,恐惧和难以置信。
Still, when most people hear a diagnosis of leukemia, lymphoma or myeloma they respond with shock, fear and disbelief.
中倍镜显示多发性骨髓瘤的浆细胞与正常浆细胞很相似,但分化较差。
At medium power, the plasma cells of multiple myeloma here are very similar to normal plasma cells, but they may also be poorly differentiated.
免疫脾细胞与骨髓瘤细胞融合后接种12块96孔板。
Confluenced immune spleen cells were inoculated in 12 plates with 96 Wells each.
目的研究白细胞介素- 2 (IL - 2)和白细胞介素- 18 (IL - 18)诱导自然杀伤(NK)细胞活化和抗骨髓瘤细胞活性的协同作用。
Objective To explore potential synergetic effects of interleukin-2 (IL-2) with IL-18 on induction of natural killer (NK) cell activity against myeloma cells in vitro.
结果:与NS1骨髓瘤细胞同一孔池中培养的DC的数目减少,形态改变,抗原递呈功能下降。
Results: the number of DC which were cultured in the same Wells with NS1 tend to decrease, the cellular appearance changed and the ability of presenting antigen decreased.
鉴于这个目的,他通过统计学方法对一群多发性骨髓瘤病人的细胞发生的变化进行了分析。
For this purpose, he has analyzed, by means of statistical methods, the cytogenetic changes in a group of patients with MM.
结论:同一孔池中培养,NS1骨髓瘤细胞抑制DC的增殖和功能。
Conclusion: NS1 myeloma cells could depress the proliferation and function of DC in the same cultured Wells in vitro.
本文对病理检查和临床确诊的19例神经母细胞瘤患者的血象及骨髓象进行了观察。
Bone marrow and peripheral blood pictures were studied in 19 pathologically or clinically proved cases of neuroblastoma.
从这个病例中得到的教训是,在器官移植后的严重免疫抑制状况下,暂时性血细胞恶液质可以有类似多发性骨髓瘤样的表现。
The lesson to be learned from the present case is that a transient plasma cell dyscrasia may present like multiple myeloma in the setting of heavy immunosuppression after organ transplantation.
目的观察供体白细胞输注(DL I)治疗急慢性白血病和多发性骨髓瘤的疗效和安全性。
Objective To observe the therapeutic efficacy and safety of donor leukocyte infusion (DLI) in acute, chronic leukemia and multiple myeloma.
新鲜的脾细胞用来与骨髓瘤细胞进行融合。
The fresh spleen cell was used for fusion with myeloma cell.
目的研究多发性骨髓瘤(MM)细胞脑源性神经营养因子(BDNF)的表达水平及其与MM细胞诱导的血管新生的关系。
Objective To investigate the expression of brain-derived neurotrophic factor (BDNF) in multiple myeloma (MM) cells and the correlation between BDNF and MM angiogenesis.
结果:对各类型白血病、多发性骨髓瘤、骨髓转移癌、部分恶性组织细胞病及疟疾可确诊。
Results: Various types of leukemia, multiple myeloma, malignant histiocytosis, bone marrow metastatic tumors and malaria can be identified by bone marrow examination.
方法采用三色免疫荧光直接标记法及多参数流式细胞术分析13例多发性骨髓瘤的免疫表型。
Methods Three-colour direct immunofluorescence staining and multiparameter flow cytometry were used for analysis of 13 samples of immunophenotyping of multiple myeloma patients.
方法对69例恶性淋巴瘤具有骨髓侵犯的骨髓细胞分类及外周血白细胞检验结果作回顾性分析。
Methods Retrospective review of the results of bone marrow smear and peripheral blood leucocyte in 69 cases of malignant lymphoma with bone marrow involved.
方法:采用小鼠淋巴瘤细胞试验(MLA)和小鼠骨髓微核试验(MNT)。
Method: Mouse lymphoma assay(MLA) and mouse bone marrow micronucleus test(MNT) were used.
末次免疫后3天取免疫小鼠脾细胞与小鼠骨髓瘤细胞SP2/0进行融合。
Splenocytes from immunized mice were fused with SP2/0 murine myeloma cells on Day 3 after the last injection.
贵科室在过去半年内,新诊断的年轻骨髓瘤患者(65岁或以下)进行自体造血干细胞移植的比例是多少?
How many percentage of newly-diagnosed MM young patients ( <65 years old) received ASCT in your department in the half past year?
目的:神经母细胞瘤的高转移尤其以骨髓转移的机制尚不清楚。
Objective: The mechanism of high metastasis rate of neuroblastoma especially metastasis to bone marrow is still unknown.
目的研究白细胞介素6 (IL 6 )依赖型人骨髓瘤细胞系XG7中IL 6信号转导途径活化与生物学效应之间的关系。
Objective To investigate the relationship between IL 6 signal transduction and its biological function on a human IL 6 dependent myeloma cell line XG 7.
目的探讨浆细胞性骨髓瘤(PCM)的骨髓组织与细胞学类型特点及临床意义。
ObjectiveTo study the characteristics histologic and cytologic features and clinical usefulness of plasma cell myeloma (PCM) subtyping according to WHO PCM classification.
结论:骨髓浆细胞增殖及尿链蛋白产生可能是多发性骨髓瘤肾脏损害的主要原因。
Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma.
结论:骨髓浆细胞增殖及尿链蛋白产生可能是多发性骨髓瘤肾脏损害的主要原因。
Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma.
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