目的观察透骨消痛胶囊干预骨性关节炎软骨下骨重塑的作用及机制。
Objective to observe the effect of Tougu Xiaotong granula (TGXT) on subchondral bone remodeling and investigate the mechanism.
口服双磷酸盐类药物是治疗该病的主要方法，但长期使用这些药物可能会抑制骨重塑，从而导致罕见的骨折，其使用风险令人担忧。
Oral bisphosphonates have become a mainstay of treatment, but concerns have emerged that long-term use of these drugs may suppress bone remodeling, leading to unusual fractures.
椎弓根内骨的重塑和骨在螺钉上的生长可能导致这个结果。
The remodeling capacity of pedicles and overgrowth of bone on screws may have an effect on this result.
你在一生中或跑或走，骨骼就会产生微小的裂缝，因此骨骼需要新生骨来重塑和替代以保持骨骼的完整性。
"As you run or walk throughout life, microcracks develop in bone," he explained. "Therefore, bone remodeling and replacement with new bone is required to maintain skeletal integrity."
你在一生中或跑或走，骨骼就会产生微小的裂缝，因此骨骼需要新生骨来重塑和替代以保持骨骼的完整性。
"As you run or walk throughout life, microcracks develop in bone," he explained. "Therefore, bone remodeling and replacement with new bone is required to maintain skeletal integrity."
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