目的弥补珊瑚无骨诱导活性、成骨能力弱等缺陷。
骨诱导活性是指移植组织通过诱导受体组织的间充质细胞向成骨细胞分化。
The latter is a process whereby the transplanted tissue induces mesenchymal cells of the recipient to differentiate into osteoblastic cells.
目的弥补单纯珊瑚无骨诱导活性、骨修复能力弱等缺陷，为临床提供理想的骨移植替代材料。
Objective To improve the osteoinduction of coral and provide a perfect bone graft substitute for clinical bone defects.
目的：弥补单纯珊瑚无骨诱导活性、骨修复能力弱等缺陷，给临床提供一种良好的骨移植替代材料。
Objectives: to improve the repairing ability of coral and creat a perfect bone graft substitute to clinical bone defects.
自体骨移植，包括松质骨和皮质骨，通常现采现植并具有成骨活性，可以提供骨生成细胞或者具有骨诱导活性。
Autografts, both cancellous and cortical, are usually implanted fresh and are often osteogenetic, whether by providing a source of osteoprogenitor cells or by being osteoinductive.
一个理想的骨移植替代材料必须提供骨传导支架、骨诱导性生长因子及具有成骨活性的祖细胞。
An ideal bone-graft substitute must provide scaffolding for osteoconduction, growth factors for osteoinduction, and progenitor cells for osteogenesis.
目的：研究人脱细胞骨复合经诱导的骨髓基质细胞的实验效果，观察细胞的黏附和生长情况，并对其成骨活性进行检测。
OBJECTIVE: To investigate the experimental effect of HAB loaded with induced BMSCs, and observe the cellular adherence and growth as well as detect its osteoblastic activity.
骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质，因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨，在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
成骨诱导后检测碱性磷酸酶(ALP)活性，RT - P CR分析其成骨相关基因的表达情况。
Alkaline phosphatase (ALP) activity was assayed as well as to assess gene expression by RT-PCR.
其它添加剂例如生物学活性剂可以添加到所述骨诱导组合物中。
Further additives such as bioactive agents may be added to the osteoinductive composition.
结论：无机活性诱导元素骨组织工程支架材料具有良好的细胞亲和性，是一种较为全面的极具潜力的骨修复材料。
Conclusions: the inorganic active element induced bone scaffold materials possess preferable cellular affinity, which could be the high potential scaffold material of bone tissue engineering.
有趣的是，似乎成骨细胞中的胰岛素信号通过刺激破骨细胞活性诱导骨钙素活性。
Interestingly, it appears that insulin signaling in osteoblasts induced osteocalcin activation by stimulating osteoclast activity.
结论：釉基质蛋白可作为一种成骨诱导剂，能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
结论：釉基质蛋白可作为一种成骨诱导剂，能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
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