现对化学基因组学研究的典型方法,以及对基于药物作用靶标的分子设计的影响作一介绍。
This article introduces the typical methods of chemogenomics research and its effect on molecular designing in view of target.
当代药物设计是通过阐明药物与靶标相互作用的机理,对药物先导化合物进行改造和优化。
Drug design is based on the mechanisms of the drug and target interaction to achieve optimization of the leads.
该文综述了药物靶标的发现、基于靶标的药物设计及其在新药研究中的应用前景。
This article reviews the drug target's discovery, drug design based on targets, as well as prospects in developing novel drug.
利用晶体X射线衍射的方法获得药物与靶标复合物的结构,为药物设计提供最直接有力的依据。
The structures of drug-target complexes obtained by X-ray crystallography provide direct and convictive evidences for drug design.
以三角形靶标的视觉锐度为基准,设计了无缝三角形网格划分算法,对典型识别概率的实测红外目标图像进行了等效三角形划分,确定了目标对应的等效三角形数目;
The infrared target in the real background were closely meshed into many equivalent triangle patterns by considering visual acuity, and the number of triangle pattern was statistically determined.
本文从工程应用的角度,全面阐述了水声靶标系统的模拟前端部分——水声靶标系统预处理机的设计思想和具体实现。
From an engineering point of view, this paper makes a full exposition of the design idea and concrete realization of the UATS preprocessor, that is, the analog front end of the UATS.
针对这个需要,本课题设计了能够模拟目标红外特性的智能红外靶标系统。
This subject is to develop a intelligent infrared target system which can simulate infrared features of objects for such purposes.
针对这个问题,提出了一种基于双重交比不变的线结构光视觉传感器的标定方法,设计了相应的标定靶标。
To address this problem, a method basing on the invariance of double cross ratio is proposed for calibrating structured-light-stripe vision sensor, and the calibration target is designed.
模拟抑制剂与靶标分子的结合作用是计算机辅助药物设计的关键部分。
Modeling interaction between inhibitor and target molecule is a key step in CADD.
网络靶标概念指的是将病证生物分子网络当作靶标,由此设计和预测最佳的药物干预方式。
The network target treats a disease-specific biomolecular network as a target to help design and predict the best possible treatments.
网络靶标概念指的是将病证生物分子网络当作靶标,由此设计和预测最佳的药物干预方式。
The network target treats a disease-specific biomolecular network as a target to help design and predict the best possible treatments.
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