如西非人以及他们的后代易患一种叫做镰状细胞性贫血的疾病,这种病在西非之外几乎都没人听说过。
West Africans, and people of West African descent, are susceptible to a disease called sickle-cell anaemia that is virtually unknown elsewhere.
这些疾病大多起源于糖与脂肪过量摄入以及久坐的习惯,但也包括镰状细胞症(这种血液病变是导致非洲儿童非传染性疾病死亡的最大杀手),这种病很容易治疗,但几乎常常都得不到确诊。
But they also include sickle-cell disease, a blood disorder that is the biggest non-communicable killer of Africa’s children. It is easily treatable, but almost always goes undiagnosed.
免疫功能低下者、脾脏移除者、镰状细胞病患者、或因肾衰而使用糖皮质激素的患者也处于该疾病的高风险中。
You are also at higher risk if you have a weakened immune system, have had your spleen removed, are on corticosteroids because of kidney failure or have a sickle cell disease.
或检测血液细胞是否有镰状细胞性贫血,白血病或其他疾病的迹象。
Or blood cells may be examined for signs of sickle-cell anemia, leukemia, or other disorders.
镰状细胞性贫血是最流行的遗传性疾病之一,具有很高的发病率和死亡率。
Sickle-cell anemia is one of the most prevalent hereditary disorders with prominent morbidity and mortality.
高风险状态包括:哮喘,镰状红细胞贫血,艾滋病毒感染,慢性心脏疾病,等等。
High risk conditions included asthma, sickle cell disease, HIV infection, and chronic cardiac disease, among others.
这些变异包括包囊纤维症、血友病、镰状细胞贫血症和其他多种疾病。
These disorders may include cystic fibrosis, hemophilia, sickle cell anemia, and many others.
镰状细胞性贫血和亨庭顿综合症就是这样的疾病,单个变异起了很大的作用。
Examples of so-called SNP diseases are sickle-cell anemia and Huntington's disease, where a single variant or mutation has a dramatic effect.
镰状细胞性贫血和亨庭顿综合症就是这样的疾病,单个变异起了很大的作用。
Examples of so-called SNP diseases are sickle-cell anemia and Huntington's disease, where a single variant or mutation has a dramatic effect.
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