细胞对外界信号可能会发生不同的反应，但这些反应都源自，配体和受体结合这个简单的化学过程。
There's a diverse range of responses that might occur, but that response is initiated by this simple chemical process of a ligand binding to a receptor.
突变受体功能下降或丧失是由于与配体结合改变或在膜上表达缺陷。
The mutant TSHRs show reduced or no function because of either altered ligand binding or defect in membrane expression.
目的确定人成纤维细胞生长因子受体1 (FGFR1)的配体精细结合位点。
Objective to determine fine binding site of ligand to fibroblast growth factor receptor 1 (FGFR1).
应用亲和毛细管电泳(ace)分析方法，对表皮生长因子受体(EGFR)和新多肽配体GE11之间的结合能力进行分析。
The binding ability of new peptide ligand GE11 and epidermal growth factor receptor (EGFR) was analyzed by affinity capillary electrophoresis (ACE) method.
为明确人体胃组织是否存在褪黑素受体(MR)，应用放射配体结合法检测人体胃组织MR特异结合量。
To determine whether melatonin receptors (MR) exist in human stomach, specific binding of melatonin receptor in human stomach was measured by radioligand binding assay.
建立具有正常极低密度脂蛋白（VLDL）受体结合功能的小分子受体片段模型并借助此模型研究VLDL受体与配体结合的作用机制。
The purpose of the paper is to build a module of small molecular receptor fragments charactering normal VLDL-R binding function and study the mechanism of VLDL-R binding to ligand.
它们的这些生物学功能是通过配体与受体结合的方式来发挥的，而CXCR3与CCR5是RA中趋化因子的标志性受体。
All of these biological effects are performed by binding of ligands to receptors. Elsewhere, CXCR3 and CCR5 are mark chemokine receptors in RA.
当学习生理学的时候，我对于配体产生了兴趣，我更加感兴趣于这些配体如何通过与不同的受体结合而导致了我们的许多行为。
While studying physiology, I became interested in ligands and how the binding of ligands to their specified receptors induces our many behaviors.
当配体与特定的受体结合，他能稳定蛋白构象，通过打开(或关闭)分子开关控制细胞内不同的分子功能。
When ligands bind to a specific subset of receptors, the ligands stabilize specific protein conformations, turning on (or off) molecular switches that control diverse cellular functions.
方法：结合国外文献简述组胺h 4受体配体作用机制的研究进展以及药物治疗的前景。
Methods By combining the foreign literatures, the progress in the mechanism research of histamine H4 receptor ligands and the prospect of drug therapy with H4 receptor ligands are introduced.
这些在三维空间分布的排除体积有利于限制配体的柔性旋转，使其采取最佳的构象与受体的配体结合区匹配。
These EVs'combined effort restricts the flexibility of the compounds and thus could reflect the best conformation with which the ligands interact with the receptor.
作者采用放射配体分析法，检测了小鼠脾细胞CRF特异性结合受体。
A radioligand assay for CRF receptor of mouse splenocytes was developed using125I-Tyr-CRF as the ligand.
作者采用放射配体分析法，检测了小鼠脾细胞CRF特异性结合受体。
A radioligand assay for CRF receptor of mouse splenocytes was developed using125I-Tyr-CRF as the ligand.
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