• 本文综合近年文献,对微透析技术基本原理以及抗菌药物动学研究中的应用一综述。

    In this paper, basic principle and application of microdialysis in pharmacokinetic and pharmacodynamic studies of antimicrobials are reviewed.

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  • 结果葡萄柚改变许多药物动学使浓度升高引起临床意义的食物-药物相互作用

    Results: Grapefruit juice can change the pharmacokinetics of a broad range of medicines and increases the blood concentrations of drugs, therefore, induces clinical food drug interactions.

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  • 可以利用药物改变某种毒剂动学性质。

    Drugs may be utilized to alter the pharmacokinetic profile of a toxicant.

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  • 现对作用机制药动学临床应用不良反应药物相互作用等做一综述

    This paper summarizes the mechanism, pharmacokinetics, clinical application, adverse reactions and drug interactions of lenalidomide.

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  • 目的介绍老年动学变化及合理使用药物

    OBJECTIVE To introduce the pharmacokinetics and pharmacodynamics of gerontic and rational administration of drug.

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  • 目的建立单室模型药物血管外多剂量给吸收和清除药动学残数法计算方法

    Objective To establish a feathering method for processing the pharmacokinetic parameters of mono-compartment drugs administered by non-parenteral route by repeated doses.

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  • 药物浓度对时间数据作房模型统计解析求出相应的动学参数

    Analysis of the data was executed by compartmental model and statistical moment calculation from which pharmacokinetic parameters were obtained.

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  • 药物开发初期,就将药动学性质不佳实体剔除出去具有十分重要意义。

    It is of great importance to identify the new chemical entity (NCE) with poor pharmacokinetic properties early in drug discovery pipeline.

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  • 综述托拉·塞米理作用药动学临床应用、药物不良反应药物经济

    The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and pharmaco economics of torasemide are reviewed.

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  • 许多药物相互作用分为的、动学的三种。

    Most drug interactions can be classified as pharmacodynamic, pharmacokinetic, or pharmaceutical.

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  • 本发明应用药动学模型模型确定药物制剂和最适施用参数

    A pharmacokinetic and pharmacodynamic model is employed to determine optimum drug formulations and optimum parameters for administration.

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  • 新型非典型抗精神病帕利酮、伊洛阿塞那平作用机制动学临床应用药物相互作用不良反应进行简要介绍。

    The mechanism of action, pharmacokinetics, clinical application, drug interactions, and adverse reactions of new atypical antipsychotics paliperidone, iloperidone, and asenapine were reviewed.

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  • 采用固相萃取-高效液相色谱法测定血浆药物浓度,计算动学参数生物利用度

    The blood samples were collected from the rats and the plasma concentration was measured by SPE-HPLC. The pharmacokinetic parameters and absolute bioavailability were evaluated.

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  • 美索·巴莫促进骨骼肌疼痛患者恢复种很好的辅助药物,现对药动学合成工艺作用临床应用安全性等做一综述

    Methocarbamol is a useful adjunct in improving patient recovery. In this article, we summarized its pharmacokinetics, synthesis, pharmacological effect, clinical use and safety.

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  • 本文就格列奈类药物动学性质及其他药物药动学相互作用一综述。

    Pharmacokinetics of glinides and pharmacokinetic interactions with other drugs are reviewed in this paper.

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  • 文中维拉唑酮的理作用动学临床评价安全性以及药物相互作用进行了综述。

    The pharmacology, pharmacokinetics, clinical evaluation, safety and drug interactions of vilazodone were reviewed in this paper.

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  • 目的采用高效液相-荧光色谱测定血清拉呋替丁药物浓度,研究临床推荐剂量下的健康人体动学

    OBJECTIVE To determine prazosin hydrochloride in human plasma by HPLC-MS method, and to investigate its pharmacokinetics and bioequivalance.

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  • 目的采用高效液相-荧光色谱测定血清拉呋替丁药物浓度,研究临床推荐剂量下的健康人体动学

    OBJECTIVE To determine prazosin hydrochloride in human plasma by HPLC-MS method, and to investigate its pharmacokinetics and bioequivalance.

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