目的:建立新颖的自动化检测药物溶出度方法。
Objective: To establish a novel method for fully automated dissolution testing.
目的:研究热熔挤出技术是否提高难溶性药物溶出度。
Objective: To assess if the hot melt extrusion (HME) technique enhances the dissolution of hydrophobic drugs.
分析了分散片的处方和工艺特点,及其在药物溶出度和生物利用度方面的优越性。
The formulation, technological characteristics, the superiority in drug dissolution and bioavailability of dispersible tablets are summarized.
目的:在自行研制的六通道溶出度过程分析系统上建立药物溶出度自动监测技术。
OBJECTIVE To establish process analysis method for the dissolution test of aminophylline tablets by fiber optic chemical sensor dissolution test system (FOCSDT-6).
目的研究光纤药物溶出度实时测定(FODT)仪监测复方磺胺甲恶唑片的溶出度。
OBJECTIVE To determine the dissolution rate of compound sulfamethoxazole tablets with the instrument of fiber-optic in situ dissolution testing (FODT).
目的:药物溶出度系指药物从片剂或胶囊等固体制剂或半国体制剂在规定的溶剂中溶出的速度和程度。
Objective: Drug dissolution is rate and degree of dissolution which is from solid dosage forms such as tablets and capsules so on at specified solvent.
目的:研究不同基质阿昔洛韦(ACV)外用制剂的药物溶出度,为开发新的ACV外用制剂提供依据。
OBJECTIVES: To study the dissolution amounts of aciclovir (ACV) from differently based preparations and provide the evidence for the development of new preparation of ACV.
目的:通过对诺氟沙星-PVP共沉淀物的研究,为提高难溶性药物溶出度和增大溶解度提供一些参考。
Objective: The authors studied norfloxacin PVP coprecipitate in order to provide references for difficult soluble drug to improve dissolution.
自身对照法与对照品法对药物溶出度值的作用并无显著的差异,并且自身对照法在药物溶出度的一般检验中具有比较大的应用价值。
There was no significant difference between self contrast method and race method in drug dissolution. The self contrast method might have greater application value in general detection.
本文通过分别采用自身对照法和对照品法两种方法计算同一药物不同剂型的溶出度值,来探讨自身对照法在药物溶出度测定中的实际应用价值。
This paper had discussed the application value of self contrast method in drug dissolution through comparison of self contrast method and race method in drug dissolution.
模型利用径向扩散,辅料络合作用和晶体药物的溶出度来表征多个动力学运输和络合过程。
The model characterizes many dynamic transport and complexation processes that include radial diffusion, excipient complexation and crystalline drug dissolution.
增加药物溶解度和溶出速率,是齐墩果酸新制剂研究中的主要措施。
One of the most powerful means in the development of oleanolic acid new dosage forms is to increase its solubility and drug dissolution velocity.
复方药物制剂的溶出度试验,通常采用定时取样,HPLC分离分析的办法解决。
Compound medicine preparation dissolution test usually adopt timing sampling method, such as HPLC, which split every composition from analytical solution.
使用光纤药物溶出仪应用两种标准曲线方程时,比较格列喹酮片的溶出度差异。
Comparing the difference of the dissolution of gliquidone tablets by fiber-optic dissolution test system which use two different standard curve equations.
以体外溶出度法考察不同配比PVP共聚物胶囊的药物累积溶出度。
The accumulative dissolution rate of puerarin in coprecipitates with different ratios of puerarin-phytosomes to PVP was investigated according to dissolution release in vitro.
比如,崩解度检测能被用来替代含高溶解性药物活性成分的快速崩解固体剂型的溶出度检测。
For example, disintegration could serve as a surrogate for dissolution for fast-disintegrating solid forms with highly soluble drug substances.
不同的固体分散体制备方法对药物的溶出度影响不大。
Preparation methods had little effect on the dissolution rates of daidzein solid dispersion.
目的 将难溶性药物阿德福韦酯制备成固体分散体,以增加体外溶出度。
Objective To prepare adefovir dipivoxil solid dispersion from poorly-soluble adefovir dipivoxil so as to improve its dissolution rate in vitro.
药物从固体分散体中的溶出度比原药粉末显著提高,且随着PVP比例的增加而增大。
The dissolution rate of CyA was increased dramatically after the formation of solid dispersion compared with the pure drug powder. CONCLUSION PVP can enhance the dissolution rate of CyA dramatically.
药物从固体分散体中的溶出度比原药粉末显著提高,且随着PVP比例的增加而增大。
The dissolution rate of CyA was increased dramatically after the formation of solid dispersion compared with the pure drug powder. CONCLUSION PVP can enhance the dissolution rate of CyA dramatically.
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