方法制备人血白蛋白免疫损伤性肝纤维化模型。
Method Immune complex-induced animal model of liver fibrosis was developed in Wistar rats.
方法运用猪血清腹腔注射法。诱导免疫性大鼠肝纤维化模型。
Methods Liver fibrosis model was induced by intraperitoneal injection of pig serum in SD rats.
方法分别利用CCL_4腹腔注射和皮下注射的方法制备大鼠肝纤维化模型。
Methods CCL4 was injected intraperitoneally or subcutaneously to make rat liver fibrosis model.
方法：利用猪血清诱导建立肝纤维化模型，采用比色法检测血清羟脯氨酸含量。
Methods: Experimental models were produced by repeated injections of pig serum, the contents of Hyp were measured after treatment.
方法采用皮下注射四氯化碳的方法制造肝纤维化模型，检测并分析血清IL-8的水平。
Methods:The mice fibrosis liver model was set up by hypodermic injection of carbon tetrachloride.
方法：采用四氯化碳诱发大鼠肝损伤，辅以高脂、低蛋白复合饲料和一定浓度乙醇饮料，复制肝纤维化模型。
Methods: Experimental model of hepatic fibrosis was induced by carbon tetrachloride and supplementary high-lipid and low-protein diet and alcohol-containing beverage.
方法：用鸭乙型肝炎病毒（DHBV）阳性血清反复攻击复制鸭乙型肝炎肝纤维化模型，同时用剔毒护肝方治疗，观察其对肝纤维化指标的影响。
Methods: Duck models with hepatic fibrosis were induced by duck hepatitis B Virus (DHBV) and meanwhile treated with Tidu Hugan Decoction. The indexes of hepatic fibrosis were assaged.
方法分别建立高脂饮食、低脂酒精饮食、高脂酒精饮食和四氯化碳大鼠实验性脂肪肝肝纤维化模型，用免疫组织化学方法观察造模肝组织中弹性蛋白的表达。
Methods Experimental liver fibrosis rats models of were induced by high fat diet, low fat diet plus ethanol, high fat diet plus ethanol, and carbon tetrachloride subcutaneous injection, respectively.
《国际肝病》：几种临床前期的试验研究表明，进行试验的抗肝纤维化药物对于肝纤维化动物模型并不是很有效。
Hepatology Digest: Several preclinical studies showed that experimental anti-fibrotic drugs are not effective in animal models with liver fibrosis.
结果：当归组的胶原蛋白含量低于模型组，组织病理学也显示当归能减轻肝纤维化。
Results: the level of liver collagen protein in Angelica group was than that of the model group and histopathology also show that Angelica reduced hepatic fibrosis.
通过递增乙醇浓度，日3次胃内灌注乙醇来复制酒精性肝纤维化动物模型。
The rat model of alcoholic liver fibrosis was induced by intragastric infusion of increasing concentration of ethanol 3 times per day.
结果：模型组肝切片观察显示典型的肝纤维化病理变化，肝中hyp含量明显高于空白对照组。
RESULTS: Observing a cut section of liver tissues, pathologic fibrosis changes are typical in model group, content of HYP in liver is obviously level to blank control group.
结果：模型组大鼠病理片呈肝纤维化变，贮脂细胞增生活跃，有较大量的IV型胶原沉积。
Result : Hepaticfibrosis appeared, fat-storing cells( FSCs) actively proliferated and the deposit of IV-collagen gradually increased in rat liver.
目的：探讨高脂饮食与酒精对肝纤维化的形成机制，寻求新的肝纤维化动物模型。
Objective: To establish new animal model of hepatic fibrosis with rats and to study the causative mechanism of hepatic fibrosis induced by high fat diet and alcohol.
目的通过大鼠肝纤维化动物模型，研究门冬氨酸鸟氨酸防止肝纤维化的作用。
Objective To study the role of ornithine aspartate on preventing of liver fibrosis through the rat liver fibrotic model.
结果：模型组大鼠病理片呈肝纤维化变，FSC增生活跃，有较大量的IV型胶原沉积。
Results:The pathological sections of the non-treated rat liver appeared fibrosis, and FSC proliferated actively and a large number IV-collagens deposited in the rat liver.
此文对肝组织学活检、血清学指标、影像学指标及多参数模型诊断肝纤维化的相关研究进展进行综述。
This paper will review the researches of hepatic fibrosis diagnosis by hepatic biopsy, serological indexes, imagine examinations and models included several indexes.
目的：在精密肝切片中利用乙醛激活肝星状细胞，建立一种星状细胞激活的体外模型，为研究和筛选阻抑肝纤维化发生的药物奠定基础。
AIM: To activate hepatic stellate cells (HSC) in vitro in precision-cut liver slices (PCLS) stimulated by acetaldehyde for studying and screening anti-fibrotic drugs.
目的：验证降低免疫性肝纤维化大鼠模型动物死亡率的药物肾上腺素的效果。
Objective: To testify the effect of adrenalin on the mortality of rats induced with immune fibrosis of liver.
方法采用以人血白蛋白攻击方法制备肝纤维化动物模型，放免法测定血TNF ，免疫组化法观察肝内层粘蛋白改变。
Methods The rat models of hepatic fibrosis were established by human serum albumin(HSA) injection. Serum TNF was detected by RIA method and laminin in the liver was studied by immunohistochemistry.
结果：各指标组合模型对肝纤维化程度都具有一定诊断价值，其中APAG模型和S指数模型表现较佳。
Results: Each model performed well in predicting fibrosis. APAG index and S index showed best among these models.
结果：各指标组合模型对肝纤维化程度都具有一定诊断价值，其中APAG模型和S指数模型表现较佳。
Results: Each model performed well in predicting fibrosis. APAG index and S index showed best among these models.
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