研究者们对凋亡与细胞周期的关系进行了深入而细致的研究,但对自噬性细胞死亡与细胞周期的关系却知之甚少。
The relationship of apoptosis and cell cycle has been explored deeply, but little is known about the relationship of autophagic cell death and cell cycle.
本文对自噬的过程及其在细胞存活和死亡中的作用作一综述。
This review focuses on the processes of autophagy and its roles in cell survival and cell death.
这项研究说明了EGFR–SGLT1通路通过维持细胞内的葡萄糖水平,阻止自噬性细胞死亡,从而为肿瘤细胞提供了生存优势。
This study reveals that EGFR–SGLT1 may confer a survival advantage to cancer cells by maintaining a basal level of intracellular glucose and preventing autophagy.
然而,不可能确定自噬空泡的增加是否是一种适应性反应或细胞死亡的预兆。
However, it is not possible to determine whether the increase in autophagic vacuolization is an adaptive response or a harbinger of cell death.
我们也会列出的注意事项时,必须考虑决定是否自噬是一个重要的效应细胞死亡机制。
We also list the caveats that must be considered when deciding whether or not autophagy is an important effector mechanism of cell death.
在后生动物有机体的细胞程序性死亡(PCD)中可以普遍观察到自噬现象。但它在垂死细胞的功能作用还不清楚。
Autophagy is commonly observed in metazoan organisms during programmed cell death (PCD), but its function in dying cells has been unclear.
在这里,我们评估认为,通过自噬细胞死亡发生积累的文献。
Here, we evaluate the accumulating body of literature that argues that cell death occurs by autophagy.
程序性细胞死亡有两种,包括凋亡和自噬性死亡,二者具有不同的形态学特征。
There are two morphologically distinctive forms of programmed cell death, apoptosis and autophagic cell death.
死亡的细胞,往往显示一个大型的积累,因此采用自噬体的形态称为自噬性细胞死亡。
Dying cells often display a large-scale accumulation of autophagosomes and hence adopt a morphology called autophagic cell death.
死亡的细胞,往往显示一个大型的积累,因此采用自噬体的形态称为自噬性细胞死亡。
Dying cells often display a large-scale accumulation of autophagosomes and hence adopt a morphology called autophagic cell death.
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