结论:制作的基因芯片可准确识别嗜铬细胞瘤相关的基因突变,为筛查嗜铬细胞瘤基因突变提供一种快速的方法。
Conclusions: The gene chip could accurately identify genetic mutations related to pheochromocytoma, which could provide a quick method of screening genetic mutations in pheochromocytoma.
将近半数的黑色素瘤患者都有BRAF基因突变,从而导致黑色素肿瘤细胞继续生长。
About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.
在实验室,他们用病毒感染那些细胞,这种病毒携带有能产生T细胞受体的基因,在这个例子中,实质上就是产生黑色素瘤导归器的基因。
In the lab, they infected those cells with a virus carrying genes that create T-cell receptors, essentially homing devices for, in this case, melanoma.
研究人员用一段被他们进行基因编码的基因重组病毒感染T细胞,这段基因编码是能够识别黑色素瘤细胞的受体蛋白的。
They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.
Plexxikon之所以能开发出这种药物,是因为研究人员利用基因测序仪绘出了黑色素瘤细胞的基因组,并发现了一个关键的突变。
Plexxikon was able to develop the drug because researchers using a gene sequencing machine had mapped the genomes of melanoma cells and found a key mutation.
这一基因也能促使细胞形成畸胎瘤,但它在干细胞从开始去变成特定细胞类型的路上不仅仅只有一次作用。
The gene also allows cells to form teratomas, but it is not active once a stem cell starts down the road to becoming a specialized cell type.
目的S100A4基因在神经母细胞瘤早期转移中发挥重要作用。
Objective S100A4 gene plays an important role in neuroblastoma cell invasion and metastasis.
所谓高危的视网膜母细胞瘤是指有特定基因突和在初诊时就发现了肿瘤扩散。
Neuroblastoma is considered high risk if the tumors have certain genetic mutations or have already spread when the cancer is diagnosed.
目的:探讨B7 -1基因修饰的肿瘤细胞作为瘤苗对小鼠胃癌的治疗效果。
Objective: To explore the therapeutic effects of the vaccine, B7 1 gene modified tumor cells, on gastric cancer in mice.
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
转EM13组小鼠与未转染组小鼠的瘤体重量和血管密度无明显差别,说明转EM13基因对H22细胞的致瘤能力可能没有影响。
Mice inoculated with H22 cells which transfected with EM13 have no difference with the mice of non-transfected group, which suggests that EM13 gene has no effect on the tumorgenesis of H22 cells.
提示在大多数视网膜母细胞瘤中,Rb基因的蛋白质产物缺乏。
The results suggest that Rb gene activity is possibly decreased in most cases of RB.
细胞受体基因重排的检测在皮肤T细胞淋巴瘤的发病机制研究、分类、诊断、判断预后上有重要的作用。
The detection of TCR gene rearrangement has an important role in the study of the pathogenesis, classification, diagnosis and monitoring of prognosis of CTCL.
结论体外转染白喉毒素a基因可杀伤人肺腺癌细胞并降低人肺腺癌细胞的致瘤性。
Conclusion: Transfection of DTA gene in vitro may kill human lung adenocarcinoma cells and reduce the oncogenicity of human lung adenocarcinoma cells.
动物实验观察放射线灭活后基因瘤苗细胞的抗肿瘤免疫作用。
Cell DNA cycle was analysed by FCM and anti tumor immunity induced by inactivated gene vaccine was observed in experimental models.
研究了电场强度、脉冲宽度、脉冲次数等电场参数对基因转化频率的影响和小鼠杂交瘤细胞最适电转移条件。
Electrical parameters affecting gene transfer, such as the field strength ( Voltage ), pulse durations and pulse frequency ect. and optimum transfer conditions in murine hybridoma cells were studied.
目的:研究LRRC4基因在恶性脑胶质瘤细胞系中的表达情况。
Objective To examine the expression absence of LRRC4 gene in glioblastoma cell lines.
目的研究p 16基因改变与脑胶质瘤恶性程度分级及肿瘤细胞增殖活性之间的关系。
Objective To study the relationship between P16 gene modification and the malignant grades of brain glioma and the proliferation activity of tumor cells.
目的利用已经建立的胶质瘤细胞诱导分化相关基因表达谱,筛选胶质瘤恶性进展相关基因。
Objective To screen out genes associated with malignant progression of glioma, based on the established glioma cell differentiation-inducing gene expression profiles.
目的探讨胶质瘤细胞ING1基因表达水平及其与肿瘤细胞增殖活性和凋亡程度的关系。
Objective to investigate the expression level of ING1 gene and their effects on cell proliferation activity and apoptosis degree in human gliomas.
目的研究P 16基因改变与脑胶质瘤恶性程度分级及肿瘤细胞增殖活性之间的关系。
Objective To study the relationship between P16 gene modification and the malignant grades of brain glioma and the proliferative activity of tumor cells.
在所分析的8例骨巨细胞瘤中,PCR均检测到PTEN基因的外显子。
Extrons of PTEN gene were detected by PCR in all of 8 cases.
目的研究次级淋巴组织趋化因子(SLC)基因转染对小鼠恶性黑色素瘤细胞生物学特性的影响。
Objective To investigate the effects of secondary lymphoid organ chemokine (SLC) gene transfer on the biological characteristics of murine melanoma cells.
目的探讨PEX基因在体外对鼠黑色素瘤细胞B16 F10生物学性状的影响。
Objective To study the effects of PEX gene on the biological characters of mouse melanoma cells (B16F10) in vitro.
由正常和突变的IDH1和IDH2基因产生的蛋白的酶活性采用用这些基因转染的培养的胶质瘤细胞检测。
The enzymatic activity of the proteins that were produced from normal and mutant IDH1 and IDH2 genes was determined in cultured glioma cells that were transfected with these genes.
脑膜血管外皮细胞瘤和间叶软骨肉瘤是一样的吗?:一项关于HEY1 - NCOA2融合基因的研究。
Are meningeal hemangiopericytoma and mesenchymal chondrosarcoma the same? : a study of HEY1-NCOA2 fusion.
目的:研究T细胞在巨噬细胞游走抑制因子(MIF)基因修饰的瘤苗诱导抗肿瘤免疫反应中的作用。
Objective: To investigate the role of t cell in the antitumor immune responses induced by MIF gene modified tumor vaccine.
目的探讨脑星形细胞瘤中cd K 4基因蛋白的表达,及其与星形细胞瘤病理学分级关系。
Objective to discuss the expression of CDK4 gene in astrocytoma, and the relationship between it and pathological classification.
探讨IL-18基因转染对大鼠C6胶质瘤细胞生长特性的影响。
To explore the effects of IL-18 gene transfection on the proliferation of C6 glioma cell.
探讨IL-18基因转染对大鼠C6胶质瘤细胞生长特性的影响。
To explore the effects of IL-18 gene transfection on the proliferation of C6 glioma cell.
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