结论：朊蛋白106- 126肽段能够诱导分化后的PC 12细胞凋亡，具有明确的毒性作用。
Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.
结论：朊蛋白106- 126肽段对分化PC 12细胞具有毒性作用，能量代谢障碍可能是其毒性作用机制之一。
Conclusion: Prion protein 106-126 peptide has cellular toxicity effect on differentiated PC12 cells, and the energy metabolize disorder may be one of the reasons for the toxic mechanism.
目的：研究朊蛋白106-126肽段在细胞水平上的毒性作用。
Objective To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells.
令人惊讶的是，根据这项新的研究，用未感染过的脑组织均浆包被的金属丝也能够在细胞培养中引发感染性朊蛋白疾病，并可使小鼠感染。
Surprisingly, according to the new research, wires coated with uninfected brain homogenate could also initiate prion disease in cell culture, which was transmissible to mice.
令人惊讶的是，根据这项新的研究，用未感染过的脑组织均浆包被的金属丝也能够在细胞培养中引发感染性朊蛋白疾病，并可使小鼠感染。
Surprisingly, according to the new research, wires coated with uninfected brain homogenate could also initiate prion disease in cell culture, which was transmissible to mice.
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