例如,某些蛋白质的过量会导致细胞异常增殖并癌变;胰岛素蛋白质的缺乏会导致糖尿病。
For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.
在与NF1相关的肿瘤中神经纤维蛋白表达的丧失与RAS活性升高和细胞增殖增加有关。
Loss of neurofibromin expression in NF1-associated tumors is associated with elevated RAS activity and increased cell proliferation.
相反,miR-17~92是通过帮助缺乏肿瘤抑制Rb蛋白的细胞增殖而发挥作用的。
Rather, miR-17~92 acts to help cells that lack the tumor-suppressing Rb protein to proliferate.
提示该活性蛋白属于蛋白酶,可能是细胞增殖信息传递链的组分或是使传递链组分活化的物质。
It suggests that the active proteins may be proteases, and they may be the constituents of cell proliferative information transportation chain or the activators of the constituents.
目的探讨热休克蛋白70 (HSP70)在创伤愈合及细胞增殖中的作用。
Objective To study the role of heat shock protein 70 (HSP70) in wound healing and cell proliferation.
结论:甲胎蛋白是促进某些新生细胞或肿瘤细胞增殖的内源性物质。
Conclusion: AFP could be an endogenous substance which can enhance the proliferation of some neoplastic or tumor cells.
目的:研究极低密度脂蛋白对SD大鼠系膜细胞的促增殖作用。
Objective: To study the proliferation promotion effect of very low density lipoprotein on mesangial cells of SD rats.
采用亲和层析和离子交换层析分离纯化,以细胞增殖实验测定表达蛋白的生物活性。
Affinity chromatography and ion exchange chromatography were applied in isolation and purification, and the bioactivity of expression protein was determined in cell proliferation test.
背景:细胞周期调控蛋白水平及其相互关系是良恶性细胞增殖的主要区别标准。
BACKGROUND: the different level of proteins regulating cell cycle and their correlation is the main criteria to differentiate the benign and malignant cellular proliferation.
细胞是否发生持续增殖依赖于它们表面的敏感受体蛋白的活性。
Whether t cells continue to multiply depends on the action of sensitive receptor proteins on their surfaces.
NF1相关的肿瘤或NF1 缺陷小鼠细胞中神经纤维蛋白的不表达与RAS的活性增加和细胞增殖的增多有关。
Loss of neurofibromin expression in NF1-associated tumors or NF1-deficient mouse cells is associated with elevated RAS activity and increased cell proliferation.
结论CSHP对C3A细胞的增殖和蛋白合成功能有促进作用。
Conclusion CSHP can promote the proliferation and synthesis of C3A cell.
结论磷酸化酪氨酸蛋白可以促进NSCLC细胞的增殖生长,是NSCLC肿瘤发生的重要途径之一。
Conslusions The phosphotyrosine protein can promote NSCLC multiplication and growth, which is one of significant pathways that lead to NSCLC development and progression.
目的观察氟对牙胚细胞增殖及相关调控蛋白表达的影响。
Objective to investigate the effect of fluoride on human tooth-germ cell proliferation and expression of related regulators.
目的研究低氧培养心肌细胞分泌出的血管内皮生长因子(VEGF)蛋白对培养内皮细胞增殖和移行的影响。
Objective To study the effects of VEGF secreted by hypoxia-cultured cardiomyocytes on proliferation and migration of cultured human umbilical vein endothelial cells (HUVECs).
目的研究不同蚕丝蛋白材料对鼠胚表皮细胞的毒性及其影响细胞增殖的因素。
Objective Toinvestigate cytotoxity of silk protein materials and their effect on proliferation of rat embryoepithelial cells.
结论:染料木黄酮不是通过促进雌激素受体基因和蛋白的表达来促进成骨细胞增殖。
CONCLUTION Genistein promotes the proliferation of osteoblast not through promoting the expression of estrogen receptor gene and protein.
目的:研究高糖对正常人类系膜细胞(NHMC)增殖及金属蛋白酶2(MMP2)和金属蛋白酶9(MMP9)表达的影响及肝素对其的干预作用。
Objective: To investigate the effects of high glucose and heparin on the proliferation and expression of MMP2, MMP9 in normal human mesangial cells (NHMC).
目的:探讨壶腹癌中抑癌基因P16蛋白与增殖细胞核抗原(PCNA)表达的相关性及其与肿瘤临床病理特征的关系。
Objective:To study the expression of P16 protein and PCNA in ampullary carcinoma and its relation with its pathological features.
背景与目的:肺纤维化是一种病因复杂的疾病,以成纤维细胞过度增殖、胶原蛋白沉积为特征。
Background and Objective: The pathogenesis of pulmonary fibrosis is complicated, it is characterized with myofibroblast hyperplasia and deposition of collagen protein.
波形蛋白的表达与肌细胞增殖具有一定的关系,但不是惟一的影响的因素。
Vimentin expression has some kinds of correlations with skeletal muscle cell proliferation, but it is not the only factor that matters.
目的:研究泛素蛋白酶体抑制剂对胃癌细胞增殖和凋亡的影响。
AIM: to investigate effects of ubiquitin-proteasome inhibitor on proliferation and apoptosis of gastric carcinoma cells.
目的探讨氧合血红蛋白对体外培养的大鼠脑微血管内皮细胞增殖和凋亡的影响。
Objective to investigate the effect of oxyhaemoglobin on proliferation and apoptosis of cultured rat brain microvascular endothelial cells.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导,调节细胞增殖、生长、分化及炎症发生等。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
结论:骨髓浆细胞增殖及尿链蛋白产生可能是多发性骨髓瘤肾脏损害的主要原因。
Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma.
结论:GLP鄄1可促进大鼠胰岛细胞胰岛素基因的表达和蛋白的分泌,对大鼠胰岛细胞亦有明显的促增殖作用。
Conclusion: GLP-1 can not only increase the insulin gene expression and insulin secretion, but also stimulate the proliferation of islet cells.
目的:研究外源性牛血浆纤维粘连蛋白对体外培养的大鼠成骨细胞增殖分化的影响。
Objective: To investigate the effects of bovine plasma fibronectin on the proliferation and differentiation of rat osteoblasts.
目的观察葡多酚(GPC)对小鼠肝细胞蛋白激酶C(PKC)和增殖细胞核抗原(PCNA)表达的影响。
Objective To study the effect of grape procyanidins (GPC) on the protein kinase C(PKC) and proliferative cell nuclear antigen (PCNA) expression in mice hepatic cells.
目的:探讨增殖细胞核抗原(pcna)和P糖蛋白在判断胃癌预后、指导化疗中的意义。
Objective: To study the role of PCNA and P-glucoprotein in distinguishing prognosis and detecting chemotherapy of gastric carcinoma.
目的:探讨增殖细胞核抗原(pcna)和P糖蛋白在判断胃癌预后、指导化疗中的意义。
Objective: To study the role of PCNA and P-glucoprotein in distinguishing prognosis and detecting chemotherapy of gastric carcinoma.
应用推荐