肿瘤干细胞学说认为，肿瘤组织中也存在少量具有干细胞性质的肿瘤干细胞，肿瘤干细胞是肿瘤发生、转移和复发的关键。
The theory of cancer stem cell proposes that the tumor tissue has its own cancer stem cells in it and regards cancer stem cell as the key to regeneration, metastasis and recurrence.
有证据证明IGF - 2在许多肿瘤细胞中可使细胞增殖增加，抑制凋亡，增加局部浸润和转移。
There are evidences that IGF-2 increases cell proliferation, inhibits apoptosis and raises local infiltration and transfer in many tumor cells.
肿瘤干细胞是在实体肿瘤中发现的一个小的细胞亚群，其具有自我更新和分化、引发肿瘤并促进肿瘤生长、复发和转移的能力。
Cancer stem cells, a small subset of cells found in solid tumors, have the capacity to self-renew and differentiate, initiate tumors and drive tumor growth, recurrence and metastasis.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
间质细胞与细胞外基质成分构成的肿瘤微环境对肿瘤细胞的生长、浸润和转移具有重要作用。
Tumor microenvironment is composed of mesenchymal cells and extracellular matrix components, which plays an important role in the growth, invasion and metastasis of tumor cells.
结果：研究表明许多肿瘤细胞表达趋化因子CXCL12和受体CXCR4，与肿瘤细胞的迁移与转移有密切关系。
Results: Researchs indicated that various tumor cells expressed chemotactic factor CXCL12 and its receptor CXCR4, which was closely related to migration and metastasis of tumor cells.
本研究研发了一个新模型显示，中性粒细胞通过物理作用和锚定循环肿瘤细胞到内皮细胞上来调节肺转移的进展。
A novel model has been developed in this study showing that neutrophils regulate lung metastasis development through physical interaction and anchoring of circulating tumor cells to endothelium.
除此之外，肝素还能在多方面有效地抑制肿瘤细胞的成功转移，包括抑制新血管的生成和抑制肿瘤细胞的生长等。
In addition, heparin has many actions that may inhibit the metastatic process, which include inhibition of angiogenesis and tumor growth.
目的研究壳寡糖对小鼠肿瘤生长和转移的抑制作用以及壳寡糖对培养的巨噬细胞相关的细胞因子表达的影响。
Objective to study the influence of oligochitosan in inhibiting growth and metastasis of tumor in rats, and in expression of cytokines associated with macrophage.
结论壳寡糖具有良好抑制肿瘤生长和转移的作用。壳寡糖可增强巨噬细胞相关的细胞因子表达。
Conclusion Oligochitosan can inhibit growth and metastasis of tumor, and enhance expression of cytokines associated with macrophage.
STAT 3有可能成为肿瘤治疗中一个新的治疗靶位，阻断STAT 3信号传导通路可能降低肿瘤细胞的侵袭和转移、抑制肿瘤细胞生长，可为肿瘤治疗提供新的思路。
STAT3 may become a new cancer treatment target. Blocking STAT3 signal may reduce tumor cell invasion and metastasis, and inhibit tumor cell grow, which can provide a new idea for cancer treatment.
STAT 3有可能成为肿瘤治疗中一个新的治疗靶位，阻断STAT 3信号传导通路可能降低肿瘤细胞的侵袭和转移、抑制肿瘤细胞生长，可为肿瘤治疗提供新的思路。
STAT3 may become a new cancer treatment target. Blocking STAT3 signal may reduce tumor cell invasion and metastasis, and inhibit tumor cell grow, which can provide a new idea for cancer treatment.
应用推荐