就芽殖酵母细胞周期检查点调控加以介绍。
The checkpoint regulation of budding yeast cell cycle was introduced in this paper.
本文研究了DNA损伤在哺乳动物细胞中激活细胞周期检查点和引起细胞凋亡的机制。
This research focused on cell cycle checkpoints and apoptosis induced by DNAdamage in mammalian cells.
高度保守的DNA修复和细胞周期检查点通路使得细胞能够应付各种内源性或外源性因素引起的DNA损伤。
Highly conserved DNA-repair and cell-cycle checkpoint pathways allow cells to deal with both endogenous and exogenous sources of DNA damage.
多种细胞机制功能障碍将导致染色体不稳定性，包括染色体分离、DNA损伤反应、细胞周期检查点、端粒功能等。
Several factors, such as defects in chromosome segregation and DNA damage response, failure of cell cycle checkpoint, telomere dysfunction, may cause chromosomal instability.
进一步的研究表明它们事实上是DNA损伤-应答激酶，不仅仅是调控细胞周期的检查点。
However, further studies have indicated that they are actually DNA-damage-response kinases, regulating more than just cell-cycle checkpoints.
细胞对DNA损伤作出应答的一个重要过程是检查点活化(检查点激酶CHK1和CHK2使关键蛋白磷酸化，从而阻止正常的细胞周期。)
An important part of the cellular response to DNA damage is checkpoint activation - checkpoint kinases CHK1 and CHK2 phosphorylate key proteins to elicit cell-cycle blocks.
细胞对DNA损伤作出应答的一个重要过程是检查点活化(检查点激酶CHK1和CHK2使关键蛋白磷酸化，从而阻止正常的细胞周期。)
An important part of the cellular response to DNA damage is checkpoint activation - checkpoint kinases CHK1 and CHK2 phosphorylate key proteins to elicit cell-cycle blocks.
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