角膜移植手术失败的主要原因是T细胞介导的免疫排斥反应,T细胞的充分活化需要共刺激信号的协同作用。
The leading cause of corneal graft failure is T cell-mediated immune rejection. Costimula-tion has been shown to be necessary for full activation of naive T cell.
结论FK506可以在早期促进异体神经匀浆激活的巨噬细胞的凋亡,从而减少或抑制周围神经异体移植后巨噬细胞所介导的免疫排斥反应。
Conclusion FK506 can promote the apoptosis of macrophage activated by allogenic nerve homogenate and reduce macrophage-mediated immunological rejection of peripheral nerve allograft.
结论FK506可以在早期促进异体神经匀浆激活的巨噬细胞的凋亡,从而减少或抑制周围神经异体移植后巨噬细胞所介导的免疫排斥反应。
Conclusion FK506 can promote the apoptosis of macrophage activated by allogenic nerve homogenate and reduce macrophage-mediated immunological rejection of peripheral nerve allograft.
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