这些珠子是包裹在组蛋白上的DNA片段。
一旦合成,组蛋白就会进入细胞核,细胞核内的DNA片段会将组蛋白包裹起来,形成一种类似串珠或绳结的结构。
Once synthesized, the histones move into the cell nucleus, where a section of DNA wraps around them to form a structure that resembles beads, or knots, on a string.
他和其他研究多种生物的生物学家发现,这些特殊的RNA在很大程度上直接影响组蛋白的合成,组蛋白是一类与DNA结合的蛋白质。
He and other biologists studying a wide variety of organisms have found that these particular RNA's direct, in large part, the synthesis of histones, a class of proteins that bind to DNA.
组蛋白 H3与H2A,H2B,H4 共同构成了真核生物核小体的八聚体核心。
Histone H3 along with H2A, H2B, and H4 form the eukaryotic nucleosome octamer core.
H 4组蛋白就是五个组蛋白团之一。
组蛋白是涉及到调控基因的蛋白质。
Histones are proteins involved in regulating genes being turned on and off.
组蛋白是真核细胞染色体中的主要结构蛋白。
Histones are the principal structural proteins of eucaryotic chromosomes.
一种组蛋白的八聚物把DNA打包成一种叫做核小体的结构。
An octa-mer of histones package DNA into a structure called a nucleosome.
染色质由卷曲的DNA、组蛋白和非组蛋白组成。
Chromatin consists of coiled DNA bound to basic proteins called histones and non-histone proteins.
除了MHC外,6号染色体上的该区域也包含一组组蛋白基因。
In addition to the MHC, this region on chromosome 6 also contains a cluster of histone genes.
而DNA就像是一些缠绕在线轴上的线一样,缠绕在组蛋白周围。
And the DNA is wrapped around the histones like a few wraps of thread around a spool.
其中的DNA长链盘绕紧密围绕一个名为“组蛋白的蛋白质组。”
Where long strands of DNA are tightly coiled around a group of proteins called "histones."
为了逆转记忆遗失,医生在复合物中添加了组蛋白脱乙酰基酶抑制物。
To reverse the memory loss, doctors inject a compound called a histone deacetylase inhibitor.
一个小小的分子称作一个乙酰基团,它黏在一个称作h4的特殊组蛋白上。
A small molecule called an acetyl group attaches to a particular histone known as H4.
表观遗传标记,例如组蛋白修饰,对于机体细胞的分化也很重要。
Epigenetic marks, such as the modifications of the histones, are also important for the specialisation of the body's cells.
这种改性或者是甲基增至DNA中,或者是乙酰基增加到组蛋白中。
This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.
组蛋白是染色质的核心,其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
组蛋白既保护DNA也在它们与DNA结合形成染色质时调节基因表达。
Histone proteins both protect DNA and regulate genes as they combine with DNA to form chromatin.
组蛋白在水中很容易溶解,其水溶液呈弱酸性和碱性,加热时不立即凝结。
They dissolve readily in water, dilute acids, and alkalis but do not coagulate readily on heating.
我们的数据提供了一个在基因组功能中组蛋白甲基化和染色质组织的新观点。
Our data provide new insights into the function of histone methylation and chromatin organization in genome function.
新方法现在允许某些时候研究人员直接显示那些基因由于组蛋白而被激活或失活。
New methods now allow researchers to sometimes directly show which genes have been activated or deactivated by the histones.
当甲基加到组蛋白后,这些基团会修饰它的性质并改变它上面特定基因的表达频率。
When methyl groups are added to a histone, they modify its properties and alter the frequency at which a particular gene is expressed.
组蛋白还起到了基因开关的作用,因此它们编码的信息可以被复制并且传递到细胞的其它部位。
Histones also play a role in turning genes on so that their coded instructions can be copied and sent to other parts of the cell.
如同阿尔茨海默病鼠,增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。
As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.
它保证了H 4组蛋白有大量的乙酰基团粘附其上,所以环绕在组蛋白上的DNA能再次被翻译。
It ensures that the H4 histones have plenty of attached acetyl groups, so the DNA wrapped around the histone once again becomes available for transcription.
在染色体中,SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
在染色体中,SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
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