结论：MCP鄄1在糖尿病肾病发病机制中发挥重要作用。
Conclusion: The MCP-1 may play a pivotal pathogenic role in diabetic nephropathy.
有关糖尿病肾病发病机制的研究，人们早先关注的是肾脏系膜基质堆积和肾小球基底膜增厚。
Research on the mechanism of diabetic nephropathy was initially focused on the mesangial matrix and glomerular basement membrane.
糖尿病肾病是糖尿病的主要并发症之一，也是终末期肾衰的元凶，其发病机制至今尚未阐明。
Diabetic nephropathy (DN) is one of the main complications of diabetes, it has become the leading cause of end stage renal failure, the pathogenesis of DN has not been completely clarified so far.
糖尿病肾病是糖尿病的主要并发症之一，也是终末期肾衰的元凶，其发病机制至今尚未阐明。
Diabetic nephropathy (DN) is one of the main complications of diabetes, it has become the leading cause of end stage renal failure, the pathogenesis of DN has not been completely clarified so far.
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