目的:通过动物实验观察碳酸化羟基磷灰石水泥修复骨缺损效果的特征。
OBJECTIVE: To observe the effective characteristics of carbonated hydroxyapatite cement on repair of skeletal defect by animal experiment.
背景:碳酸化羟基磷灰石骨水泥是一种新型的骨修复材料,已应用在骨缺损临床治疗中。
BACKGROUND: Carbonated hydroxyapatite cement is a new type material for skeletal repair and hydroxyapatites have been applied in the clinical treatment of skeletal defect.
结果表明:在SBF中浸泡后,两种玻璃陶瓷表面都能生成含碳酸根的羟基磷灰石(HA)层,显示这两种材料具有良好的生物活性;
The results show that the surfaces of the two materials are covered with a layer of carbonate hydroxyapatite (HA) when soaked in SBF, which indicates they are bioactive.
成岩矿物主要为薄膜状绿泥石及加大状石英质矿物,还有自生磷灰石、充填状硅质及碳酸盐矿物。
Diagenetic minerals are mainly thin film shaped chlorite and increasing shaped quartz minerals. There are autogenous apatites, filled silicious and carbonate minerals as well.
结果:复合材料中的羟基磷灰石为类似于自然骨矿物相的弱结晶含碳酸纳米晶体,并均匀分散于有机相壳聚糖中。
Results:The HA synthesized here was poorly crystalline carbonated nanometer crystals and dispersed uniformly in chitosanp hase and there was no phase-separation between the two phases.
交联的胶原及其仿生矿化形成的碳酸羟基磷灰石可使支架具有良好的生物学性能,有望成为广阔临床应用前景的骨组织工程植入材料。
The scaffolds could have good biological properties because of the cross-linked collagen and the mineralized hydroxyapatite, and be considered as a potential bone tissue engineering implant.
交联的胶原及其仿生矿化形成的碳酸羟基磷灰石可使支架具有良好的生物学性能,有望成为广阔临床应用前景的骨组织工程植入材料。
The scaffolds could have good biological properties because of the cross-linked collagen and the mineralized hydroxyapatite, and be considered as a potential bone tissue engineering implant.
应用推荐