结果15块破裂斑块中有12例PAPP-A染色阳性，而所有不稳定斑块与稳定斑块PAPP-A染色均为阴性。
Results PAPP-A staining was positive in 12 of 15 ruptured plaques, and negative in all unstable and stable plaques.
久而久之，斑块会破裂阻塞血管。
Over time, the plaque can rupture and block the vessels altogether.
对某些病人，它可以使动脉粥样硬化斑块破裂形成冠状动脉血栓以致心脏病。
In some patients, this may alter atherosclerotic plaques and cause clots in coronary arteries leading to heart attacks.
在内外因素的共同作用下，不稳定斑块可能发生破裂、糜烂以及钙化等现象。
Under the influence of intrinsic and extrinsic mediators, vulnerable plaque may develop to rupture, erosion or calcification.
而且，运动时的动作可能会增加斑块破裂的风险，引发心肌梗死。
The act of exercising, however, may increase the risk that the plaques will rupture, precipitating a heart attack.
而且，运动可能会增加斑块破裂的风险，引发心肌梗死。
The act of exercising, however, may increase the risk that the plaques will rupture, precipitating a heart attack.
其斑块破裂背后的分子和细胞特征已经被广泛的研究。
Underlyingcellular and molecular characteristics of plaque rupture have been studied extensively.
这些炎症反应造成了斑块继续长大、破裂最终堵塞血流。
This causes inflammation that makes plaques more likely to swell, rupture and cut off blood flow.
穿通性溃疡(PAU)是指动脉粥样硬化斑块溃疡、固有层破裂，穿破动脉内膜，突入中膜。
Penetrating atherosclerotic ulcer (PAU) refers to an atheromatous plaque that ulcerates and disrupts the internal elastic lamina, extending through the intima into the aortic media.
结论高血浆甘油三酯是国人急性冠状动脉综合征患者斑块破裂的一个重要危险因素。
Conclusions High serum triglyceride level is an important risk factor for plaque rupture in patients with acute coronary syndrome in China.
斑块破裂提供了血小板聚集和血栓形成的场所，导致不稳定性心绞痛或心肌梗死。
Plaque rupture provides a focus for platelet deposition and thrombosis, and results in unstable angina or myocardial infarction.
能在不稳定冠脉斑块破裂前识别它吗？
Can We Identify Unstable Coronary Plaques Before They Rupture?
动脉粥样硬化斑块不稳定是导致斑块破裂进而引起卒中的重要原因。
The instability of atherosclerotic plaques is the important reason that may result in plaque rupture and then cause stroke.
评价血清mmp 9及TIMP 1水平作为粥样斑块破裂的血清学指标的意义。
To evaluate significance of serum levels of MMP-9 and TIMP-1 as serum target of plaque rupture.
预防动脉粥样硬化斑块破裂是预防急性冠脉综合征的最主要手段。
Therefore, to prevent plaque rupture of coronary atherosclerosis is one of the most important methods for preventing ACS.
动脉粥样硬化斑块的不稳定是导致斑块破裂、溃疡致使动脉内血栓形成从而引起卒中的主要发病机制，具有极大的危害性。
The instability of atherosclerotic plaques is the leading pathogenesis of stroke resulting in plaque rupture and ulcer-caused thrombosis and it is very harmful.
急性冠状动脉综合征发生的主要病理生理机制系粥样斑块破裂。
The principal pathophysiological mechanism of acute ischemic coronary syndrome(AICS) is atherosclerotic plaque rupture.
一旦斑块破裂，将导致心脏和脑部供血不足，触发心脏病或中风。
If a plaque ruptures, it can block blood flow to the heart or brain, causing heart attack or stroke.
急性冠状动脉综合征是由于纤维斑块破裂引发冠状动脉内血栓而导致的。
The disruption of the fibrous cap of vulnerable coronary atheromatous plaques leads to intracoronary thrombosis and acute coronary syndrome.
目的探讨血管内超声(IVUS)对斑块破裂、血栓形成的诊断价值。
Objective To explore the value of intravascular ultrasound (IVUS) in diagnosing plaque disruption and arterial thrombosis.
冠状动脉不稳定斑块破裂继发急性血栓形成是ACS的主要病理基础。
Acute coronary thrombus formation secondary to vulnerable atherosclerotic plaque is the main pathological basis of ACS.
他汀类药物能够稳定斑块，同时也能减轻炎症反应，而炎症恰好是斑块破裂机制的一部分。
Statins may stabilize plaques. They may also calm the inflammation that is part of the mechanics of plaque rupture.
研究背景急性冠状动脉综合征是由于不稳定斑块破裂诱发血栓形成所致。
Background Acute coronary syndromes are thought to result from atherosclerotic plaque disruption and intramural thrombus formation.
斑块纤维帽中能抵抗破裂的主要成分是基质胶原。
The resistance to rupture depend greatly on fibrous cap's content of fibrillar interstitial collagen.
因而寻找导致不稳定斑块形成与斑块破裂的危险因素具有重大意义。
It has great importance to search the risk factor that make the plaque unstable and rupture.
结论：血清mmp 2、MMP 9水平可作为动脉粥样硬化斑块不稳定或破裂的判断指标，有助于UAP的早期诊断及预后判定。
Conclusion: The levels of serum MMP-2, MMP-9 can be regarded as serum indices to judge unstable or ruptured plaque, and be helpful for early diagnosis and prognosis judgment in UAP patients.
因此，研究斑块破裂的机制及探索稳定斑块的方法具有重要临床意义。
It is, therefore, clinically very important to study the underlying cause of plaque rupture and to explore the possible method for stabilizing plaque.
因此，研究斑块破裂的机制及探索稳定斑块的方法具有重要临床意义。
It is, therefore, clinically very important to study the underlying cause of plaque rupture and to explore the possible method for stabilizing plaque.
应用推荐