近年来的研究发现，许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
因此，探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。
Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
由于该机制可影响特定抑癌基因的活性，因而与肿瘤形成密切相关。
This mechanism is particularly relevant in cancer since it can interfere with the activity of specific "suppressor" genes.
肿瘤的发生是原癌基因激活、抑癌基因失活以及凋亡相关基因失调等诸多因素综合作用的结果。
The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on.
目的：探讨壶腹癌中抑癌基因P16蛋白与增殖细胞核抗原（PCNA）表达的相关性及其与肿瘤临床病理特征的关系。
Objective:To study the expression of P16 protein and PCNA in ampullary carcinoma and its relation with its pathological features.
胃癌的发生与多基因异常表达密切相关，其中抑癌基因甲基化是胃癌发生、展的重要机制之一。
The genesis of gastric cancer resulted from abnormal expression of many genes, and methylation of the tumor suppressor genes is one of the major mechanisms of gastric carcinogenesis.
目的探讨胃癌组织中甲基化酶、去甲基化酶基因与肿瘤相关癌基因和抑癌基因的关系。
Objective To investigate the relationship of the expression of DNA methyltransferase, demethylase(mbd2) and tumor-associated genes in human gastric cancer.
而肿瘤的发生与抑癌基因和癌基因密切相关。
And the occurrence of tumor is closely related to oncogenes and anti-oncogenes.
癌基因的激活以及抑癌基因的失活被认为与细胞的恶性转化密切相关。
Transformation of cells is closely related to the inactivation of tumor-resistant genes and the activation of oncogenes.
鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标，因而一直是肺癌研究领域内的热点。
Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.
目的探讨癌基因MMP - 9和抑癌基因RECK在喉癌组织中的表达与喉癌临床特征的关系，了解喉癌的生物学行为，并研究两种基因的表达相关性。
ObjectiveTo investigate the relation between expression of MMP-9 and RECK in laryngeal carcinoma and it's clinical characteristics and to explore the biological action of laryngeal tumor.
目的探讨癌基因MMP - 9和抑癌基因RECK在喉癌组织中的表达与喉癌临床特征的关系，了解喉癌的生物学行为，并研究两种基因的表达相关性。
ObjectiveTo investigate the relation between expression of MMP-9 and RECK in laryngeal carcinoma and it's clinical characteristics and to explore the biological action of laryngeal tumor.
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