我们一直在讨论如何进入临床试验的神经干细胞。
We have been discussing how to get neural stem cells into clinical trial.
结论①小鼠下丘核区存在着具有多向分化潜能的神经干细胞。
Conclusion There existed neural stem cells in mice nucleus of inferior colliculus area.
结论个体发育不同阶段所得的神经干细胞有不同的生物学特性。
Conclusion The neural stem cells isolated from different periods of ontogeny have different biological specificities.
中心引进的神经干细胞移植技术是目前世界上最尖端的干细胞技术之一。
VSELCN is a independently innovated technique by This technology was developed by China Stem Cell Medicine Holding Co.
目的探讨人脂肪组织来源的神经干细胞移植治疗大鼠脑缺血再灌注损伤的疗效。
Objective To study the effects of neural stem cells from human adipose tissue-derived stromal cells transplantation for treatment of cerebral ischemic - reperfusion injury in rats.
新生神经元不是由成熟神经细胞产生的,而是来源于终身存在于大脑中的神经干细胞。
New neurons are born not from mature nerve cells but rather develop from neural stem cells that remain in our brains throughout life.
结论移植的神经干细胞能在PD模型小鼠纹状体存活,并可分化出特定的多巴胺能神经元。
ConclusionsThe transplanted multipotent NSCs could survive, differentiate into functional dopamine neurons in the brains of PD model mice.
研究的题目是:这些细胞系和人正常的神经干细胞是否一样,或者一种细胞系优于其它的?
The question: would the cell lines be the same and mirror the normal neural stem cells found in humans or would one cell line be superior to the other?
而HNG - E则为发生转化的神经干细胞系,但能在RA诱导下向多巴胺能神经元分化。
HNG-E cells were characterized as transformed neural stem cells, and can be differentiated into dopaminergic neurons by ra induction.
研究人员还将培养基中生长的神经干细胞移植到大鼠海马区,刺激其中已有的神经干细胞活化。
The researchers also are grafting neural stem cells grown in culture dishes into the hippocampus, to stimulate those already present.
结论:从人胚胎脑皮质成功分离培养出的神经干细胞,是研究神经干细胞诱导分化的良好模型。
CONCLUSION: NSCs are successfully isolated and cultured from human embryonic cerebral cortex. They are good models for research of inducing differentiation.
透射电镜下观察不同诱导剂诱导的神经干细胞超微结构,发现细胞的大体形态相似,但细胞器有差异。
The ultrastructure of the induced neural stem cells in the two groups was similar under the transmission electron microscope, only with some differences in organelles.
面对该区域的损伤,这些细胞已经做出反应,介导室壁内层的重建和确定应该进行修饰的神经干细胞环境。
Faced with damage in the region, these cells had responded, mediating the rebuilding of ventricular wall lining and establishing a modified neural stem cell environment.
用一个动物模型,研究者发现:与正常出生体重的新生儿对比,低出生体重儿的神经干细胞更少分支和分化。
Using an animal model, the researchers found less division and differentiation of the neural stem cells of a newborn with low birth weight as compared to normal birth weight.
科学家们的研究聚焦于出生后的神经干细胞位于侧脑室或腔的内层,在一个被称为室下区域(SVZ)的地方。
The scientists focused their study on postnatal neural stem cells that lie next to the lining of the brain's lateral ventricles, or cavity, in a region known as the subventricular zone (SVZ).
方法分离、鉴定并扩增取自10 ~ 14周药物流产胎儿大脑皮质的神经干细胞,应用pcr -ELISA法检测神经干细胞端粒酶活性。
Methods the neural stem cells were isolated, identified and amplified from the cortex of aborted human embryo with 10 to 14-week gestational age, then telomerase activity was detected by PCR-ELISA.
结果:记忆力强组小鼠海马齿状回的神经干细胞数目明显多于记忆力弱组(P<0·01),而记忆力弱组与对照组比较,其神经干细胞数目差异无统计学意义(P>0·05)。
Result:the number of neural stem cells in dentate gyrus of the mice in HMG was higher than that in PMG(P<0.01), but there was no difference between the PMG and the control(P>0.05).
体育锻炼通过一种与‘诺金’和BMP的复杂相互作用,能帮助确保神经干细胞活性和脑细胞新生。
Exercise, he says, through a complex interplay with Noggin and BMP, helps to ensure that neuronal stem cells stay lively and new brain cells are born.
让他兴奋不已的是,提取出的组织很旺盛的生长,并且最终在培养环境中的很多细胞都发现有神经干细胞特有蛋白质的存在。
To his delight, the extracted tissue thrived and grew, and many of the cells in the resulting culture did indeed contain proteins known to be characteristic of neural stem cells.
从22例样本中,他最终培养得到了16组神经干细胞,并且得出成功与否决定于受损伤的部位的结论。
He has managed to derive neural stem cells from 16 of these patients, out of a total of 22, and believes that success depends on which region of the brain is affected.
这项研究对LTB4刺激神经干细胞的细胞和分子机制也有深入研究。
The study also provided so insight into the cellular and molecular mechanisms involved when LTB4 stimulates neuronal stem cells.
STEM 121检测移植的人神经干细胞在小鼠脑的海马中的迁移和分化。
STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.
目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
方法采用细胞培养技术、免疫细胞化学方法观察新生大鼠皮层神经干细胞向胆碱能神经元定向分化的时空变化。
Observation the space-time change of cortex nerve stem cell in newborn rat orientation differentiation to cholinergic neuron by cell cultured and immunocyte chemistry methods.
方法采用细胞培养技术、免疫细胞化学方法观察新生大鼠皮层神经干细胞向胆碱能神经元定向分化的时空变化。
Observation the space-time change of cortex nerve stem cell in newborn rat orientation differentiation to cholinergic neuron by cell cultured and immunocyte chemistry methods.
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