回顾性分析了206名患者肿瘤组织鸟嘌呤转甲基酶基因的甲基化状态,MGMT。
The methylation status of the methyl-guanine methyl transferase gene, MGMT, was determined retrospectively from the tumour tissue of 206 patients.
丝状支原体中分离出特异性的甲基酶,进而用该酶甲基化酵母中提取出的丝状支原体基因组。
Specific methylase enzymes were isolated from M. mycoides and used to methylate the M. mycoides genome isolated from yeast.
同时肝微粒体蛋白含量、CYP450含量和红霉素-N-脱甲基酶活性呈现有一定的性别差异。
And the liver microsome protein content, CYP450 content and erythromycin-N-demethylase activity appear some gender differences.
他们研究了磷脂酶C抑制剂苯甲基磺酰氟对大鼠脑线粒体缺血性损伤的作用。
They studied the effect of phenylmethylsulfonyl fluoride, a phospholipase C inhibitor, on ischemic injury to brain mitochondria in rats.
了解了何种酶在去除甲基能够帮助研究者们发现更便宜更有效的方法来生产人造药物去治疗哮喘、血液以及心脏疾病。
Knowing which enzymes remove methyl groups can help researchers find cheaper, more efficient ways to produce synthetic drugs to treat asthma and blood and heart problems.
这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
所以,这次在把正常细胞放入脂肪和细胞因子之前,研究人员加入了一种能阻碍DNMT3B活动的化学物质,即一种会使PG C - 1甲基化的酶。
So, this time, before bathing the healthy cells in fats or cytokines, the team added a chemical that blocks the activity of DNMT3B, an enzyme which they found methylates PGC-1 alpha.
结果显示不论DNA甲基化与否,所有使用受体细胞限制性内切酶的基因组移植都获得成功。
When genome transplantations were performed using the restriction enzyme minus recipient cells, all the genome transplantations worked regardless of if the DNA was methylated or not.
漆酶的去甲基化作用可以使木质素降解,也能够参与自然界中花色的形成。
The demethylation of laccase is applied to lignin degradation and formation of color within natural flowers.
在经过对植物体系进行酶相对数量的调整后,研究人员会在这些酵母中加入一种名为二甲基吗啡的混合化学物质,这样就会得到纯净的吗啡。
After tweaking the system to adjust the relative amounts of the enzymes, the researchers could feed their yeast a precursor chemical called thebaine, and get pure morphine in return.
亚甲基四氢叶酸还原酶基因突变导致的遗传多态现象可增加神经管缺陷(ntd)发生的危险性。
The genetic polymorphisms due to mutations in the methylene tetrahydrofolate reductase gene may increase the risk for NTDs.
目的:研究一氧化氮合酶抑制剂N-硝基-L-精氨酸甲基酯对大鼠肠系膜淋巴管作用。
Objective: To study the effect of NG-nitro-L-arginine methyl ester, one of the inhibitors of NOS, on rats' mesenteric lymphatic vessels.
结论亚甲基四氢叶酸还原酶基因C677T基因多态性可能是我国大肠癌的遗传易感因素。
Conclusion These findings demonstrated that the genetic variation of MTHFR C677T should be a genetic susceptibility factor for colorectal cancer in a Chinese population.
甲基对硫磷水解酶(MPH)是一种新的有机磷水解酶。
Methyl parathion hydrolase (MPH) is a novel member of organophosphorus hydrolase.
在某些情况下,甲基化的酶作用物能够从隐马尔科夫模型序列相似性网络中被推断。
In some cases, the substrate of methylation can be inferred from hidden Markov model sequence similarity networks.
目的探讨焦虑症与儿茶酚邻甲基转移酶基因多态性的相关性。
Objective: To explore the association between anxiety disorder and polymorphism of catechol-O-methyltransferase(COMT).
本文中研究了添加果胶甲基酯酶对不同类型番茄酱粘度的影响。
In this paper the effects of Pectin Methyl Esterase on viscosity of tomato paste were studied.
DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
该文就近年来亚甲基四氢叶酸还原酶基因多态性与高危妊娠和胎儿畸形关系做一简要综述。
In this review, we summarized researches on the correlation between methylenetetrahydroflate reductase gene polymorphism, high-risk pregnancy and congenital anomalies.
简要论述了植物dna甲基转移酶、甲基化方式、发生位置及DNA甲基化所引起的表观遗传现象。
This article briefly discusses plant DNA methyltransferase, the mode and the loci of methylation and the epigenetic phenomenon originated by DNA methylation.
DNA甲基化及其调节酶是近年来表观遗传学研究的热点。
Recent studies on DNA methylation and its regulatory enzymes, seem hot to researches of epigenetics.
原核m酶作为模式分子,在研究和解释甲基化作用和去甲基化作用机制中起到了重要作用。
Procaryotic m enzymes as model molecule play an important role in studying mechanism of methylation and demethylation.
目的探索多巴胺d3受体(DRD3)、多巴胺d2受体(DRD2)和儿茶酚氧位甲基转移酶(COMT)基因多态性与双相情感障碍的关系。
Objective To explore the relationship between dopamine D3 (DRD3), dopamine D2 (DRD2), catechol o methyltransferase (COMT) genes polymorphism and bipolar affective disorder.
采用铁氰化钾作为媒介体,将尿酸氧化酶固定在羧甲基纤维素钠处理过的碳电极表面,研制成一种尿酸生物传感器。
An amperometric uric acid biosensor was developed by immobilizing uric acid oxidase on carbon electrodes, in which, potassium ferricyanide was used to electron medium of chemistry response.
为提高碱性磷酸酶(ALP)活性测定的灵敏度,对以4-甲基伞形酮磷酸酯(4-MUP)为底物的荧光法进行了研究。
In order to improve the sensitivity of detection of alkaline phosphatase(ALP)activity, a fluorometric method based on 4-methylumbelliferyl phosphate(4-MUP)as substrate was investigated.
甲基对硫磷水解酶(MPH)是一种新的有机磷水解酶。
Methyl parathion hydrolase (MPH) was a novel member of phosphotriesterase.
目的探讨北方乡村妇女亚甲基四氢叶酸还原酶(MTHFR)基因多态性与神经管畸形的关系。
Objective To explore relationship between methylenetetra hydrofolate reductase (MTHFR) polymorphism and neural tube defects (NTDs)of women in the northern countryside.
随着组蛋白赖氨酸去甲基化酶的发现,证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
随着组蛋白赖氨酸去甲基化酶的发现,证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
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