结论胸腺内注射异基因MHC抗原可诱导大鼠对异体坐骨神经移植的特异性免疫耐受。
Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.
结论供者特异性抗原能诱导受体免疫耐受并促进移植物存活,可望成为较理想的临床免疫耐受诱导方法。
Conclusion the donor specific antigens can induce the donor specific immunological tolerance. It may be a practicable approach for the clinical experiments in the future.
目的探索建立受体针对供体抗原特异性T淋巴细胞克隆,转入自杀基因诱导移植耐受的可行性。
Objective to explore the feasibility that the recipient against donor antigen specific t lymphocytes clones are formed, and the suicide genes are induced into the clone.
结论:口服抗原可以引起受者对异基因抗原的特异性免疫反应降低,使受者的心脏移植存活期延长。
Conclusion Oral administration of alloantigen can down-regulate the immune response to histocompatibility antigens, prolong the survival times of heart allografts.
方法:采用大鼠异位(颈部)心脏移植模型,通过门静脉途径输注不同类型供者特异性抗原。
Methods: a rat model of cervical heterotopic cardiac transplantation was established and the different donor antigens were infused through the portal vein.
方法:采用大鼠异位(颈部)心脏移植模型,通过门静脉途径输注不同类型供者特异性抗原。
Methods: a rat model of cervical heterotopic cardiac transplantation was established and the different donor antigens were infused through the portal vein.
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