每天服用质子泵抑制剂的病人受感染的风险比不服用药物的增加了74%。
Patients taking PPIs daily had a 74% increased risk compared with those not taking the drugs.
每天服用质子泵抑制剂一次以上的患者受感染的风险也会加倍，而且会导致严重腹泻。
Patients taking a more-than-once-a-day PPI dose more than doubled their risk of getting C. diff, an infection that can cause severe diarrhea.
地高辛直接抑制心肌细胞膜的钠-钾atp酶泵，导致细胞内的钠和钙的增加，进而增加心肌收缩力。
Digoxin directly inhibits the sodium-potassium ATPase pump in the membrane of the cardiac myocyte, causing an increase in intracellular sodium and calcium which increases myocardial contractility.
目前，也有其他一些市面上买得到的质子泵抑制剂。然而，他们不是一样容易转换为活化形式吗？
At the moment, there are several other commercially available proton pump inhibitors. However, they are not as susceptible to conversion into active forms?
前药的接触了强酸后被质子化，并且经过结构的改变成为真正能够抑制质子泵的活化形式。
The prodrug exposed to strong acid is protonated and undergoes a conformational change to its active form which is capable of inhibiting the proton pump.
进一步的研究显示质子泵抑制剂与波利维一起没有导致像心肌梗塞或中风等心脏病事件风险的显著增加。
Further research showed using PPIs along with Plavix did not lead to any significant increase in the risk of heart disease events like heart attack or stroke.
处方的警告和注意事项，非处方质子泵抑制剂的药品事实说明书将对这些结果进行说明。
Both the Warnings and Precautions section of the prescription labeling and the Drug Facts label on OTC proton pump inhibitors will address these findings.
质子泵抑制剂，可以处方和非处方取药，主要通过减少胃酸量而发挥作用。
Proton pump inhibitors, available by prescription and over-the-counter (OTC), work by reducing the amount of acid in the stomach.
这种质子泵抑制剂已经被批准用于12岁至17岁的青少年。
This proton pump inhibitor was already approved for adolescents between the ages of 12 to 17.
处方质子泵抑制剂用于治疗的疾病如反流性胃食管疾病(GERD)、胃和小肠溃疡、食道炎症。
Prescription proton pump inhibitors are used to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus.
但是近期的报道已经表明两种药物之间有潜在危险的相互作用，由此质子泵抑制剂降低抗血小板药物的实际效果。
But recent reports had suggested that there might be a potentially dangerous interaction between the two drug classes whereby PPIs reduce the actual effectiveness of antiplatelet agents.
当决定质子泵抑制剂用于治疗时，卫生保健专业人员和消费者应权衡这些药物的利弊。
Health care professionals and consumers should weigh the known benefits against the potential risks of proton pump inhibitors when determining if these medications are appropriate for treatment.
质子泵抑制剂可以治疗顽固性胃灼热。
Proton pump inhibitors can tackle really stubborn heartburn.
迄今为止每个质子泵抑制剂都被研究开发为一个前药的管理形式。
Every proton pump inhibitor so far developed is administered in a prodrug form.
应建议患者服用质子泵抑制剂后如果出现心律失常、抽搐、或者癫痫等症状应及时就医。这些症状可能是低镁血症的征兆。
Advise patients to seek immediate care from a healthcare professional if they experience arrhythmias, tetany, tremors, or seizures while taking PPIs. These may be signs of hypomagnesemia.
联邦机构将会要求把这个警告加到处方与非处方质子泵抑制剂的包装标签上。
The federal agency will now require the warning to be added to the package labels of both the prescription and nonprescription versions of the drugs.
由于低镁血症可能会被漏诊和漏报，现有数据还不能对接受质子泵抑制剂治疗后低镁血症的发生率进行准确评估。
However, because hypomagnesemia is likely under-recognized and under-reported, the available data are insufficient to quantify an incidence rate for hypomagnesemia with PPI therapy.
如果您长期使用非处方药类质子泵抑制剂，请务必告知您的医疗保健专业人员。
Make sure your healthcare professional knows if you have been taking an OTC PPI drug for a long period of time.
质子泵抑制试验表明，治疗有效或显著有效的病人中81%试验阳性。
Proton pump inhibit test showed that positive ratio was 81% in the patients who showed effective after treatment.
观察质子泵抑制剂和促动力药预防和治疗反流性食管炎及出血的重要性。
Observed the importance of using proton-pump inhibitor (PPI) and gastrointestinal prokinetic drug for treatment of re and prevention of bleeding.
这些处方药类质子泵抑制剂标签WARNINGSANDPRECAUTIONS部分将增加这类药物引发低镁血症风险的信息。
Information about the potential risk of low serum magnesium levels from PPIs will be added to the WARNINGS AND PRECAUTIONS sections of the labels for all the prescription PPIs.
一个最近的药物进化的例子是抑制胃酸分泌的质子泵抑制剂的进化。
One of the recent examples of such drug evolution is proton pump inhibitors that inhibit gastric acid secretion.
埃索美拉唑是新一代质子泵抑制剂成员，有较强的抑制胃酸分泌效应。
Esomeprazole is a new member of proton pump inhibitors (PPI) with strong suppressive effects on gastric acid secretion.
如果你的医生推荐你使用质子泵抑制剂，不要停止使用这个药，直到你和医生讨论是否该停药。
If your doctor recommended that you take a PPI, don't stop taking the medication until you discuss it with him or her.
目的：为质子泵抑制剂的合理应用作一全面的评述。
OBJECTIVE: To make a comprehensive comment on rational use of proton-pump inhibitors.
雷贝拉唑比前期上市的其他质子泵抑制剂可以更快速的发挥作用。
Rabeprazole exerts its action much more quickly than the other proton pump inhibitors previously developed.
艾司奥美拉唑是一种新型的质子泵抑制剂， 它是奥美拉唑的S-型光学异构体。
Esomeprazole, a new proton pump inhibitor, is the S - isomer of omeprazole.
泵抑制剂可部分逆转这种耐药性。
雷贝拉唑是一种新型的质子泵抑制剂，广泛应用于消化系统疾病的治疗。
Rabeprazole is a new type of Proton Pump Inhibitors, which is widely used in therapy for digestive system illness.
雷贝拉唑是一种新型的质子泵抑制剂，广泛应用于消化系统疾病的治疗。
Rabeprazole is a new type of Proton Pump Inhibitors, which is widely used in therapy for digestive system illness.
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