丢失互联网身份会造成很大的问题。
这个论题同样遇到了很大的问题。
膝关节炎似乎带来了很大的问题。
Osteoarthritis of the knees presents a particularly serious problem.
至此，您可能会想，长轮询和流都有一个很大的问题。
At this point you might be thinking that there is a major problem with both long polling and streaming.
他们的银行存在很大的问题，而且它们不愿面对这些。
They had huge problems in their Banks and they didn't face up to them.
产妇的高死亡率令人担忧，说明还是存在很大的问题。
The maternal mortality rate is particularly worrying, pointing to serious problems.
我在埃及，苏丹甚至埃塞俄比亚都没有遇到很大的问题。
I didn't have any serious problems in Egypt or Sudan, or even in Ethiopia.
但遗憾的是他没有“呱呱落地”，从医学角度来说，这是一个很大的问题！
But unfortunately, he didn't come with a cry, which was a big problem from the medical point of view.
他们都遇到了很大的问题，就是她们都做不到，因为树枝和果实每次都移动开了。
They both took great trouble, but they were not able to do it, for the branches and fruit both moved away from them every time.
它带来了很大的问题，因为它的爆炸力很强，而且在X射线下看不到。
And it's a problem for, so it's a very powerful explosive and you can't see it in X-rays.
无论国会采取何种措施来帮助邮政业渡过经济衰退时期，但仍然存在很大的问题。
Whatever action Congress takes to help the postal service weather the recession, a larger question looms.
进行这个讨论真的非常重要，因为这是两个差别很大的问题，答案自然也迥然不同。
It's really critical to make that distinction, since these are two very different problems Spaces with different answers.
长期的训练可以提高医生的沟通能力，但时间和资金将会成为很大的问题。
Long training sessions can boost doctors' communications skills, but finding the time and money for such instruction can be challenging.
在比赛中我发现他的确有很大的问题，但我仍然必须在比赛中做到全神贯注。
I noticed straightaway that he had a problem.I knew that, but I still had to remain very focused.
但是这里存在一个很大的问题：使用所有这些应用程序的用户并不是Web编程人员。
But here's the big problem: those users that are consuming all these apps aren't like Web programmers.
“他能否再回来是一个很大的问题。”斯坦福·伯恩斯坦公司的分析家托尼说。
“It raises the bigger question about whether he'll ever return,” said Toni Sacconaghi, an analyst with Sanford C. Bernstein & Company.
你需要注意的一个问题就是只要你是爱你的孩子的，他们就不会出很大的问题。
The most important thing is to recognize that so long as you love your kids, they’ll probably turn out OK.
你需要注意的一个问题就是只要你是爱你的孩子的，他们就不会出很大的问题。
The most important thing is to recognize that so long as you love your kids, they'll probably turn out OK.
净利率差额的紧缩，筹资成本与分配率的差距表明美国经济遇到了很大的问题。
The contraction in their net interest margin, the gap between their cost of funds and the rate at which they deploy them, underscores a larger problem in the American economy.
当应用程式满足上述的甜蜜点时，这些缺点可以被忽略不计，但是在极端情况却是很大的问题。
These weak points are minimized for applications that fall within the Rails sweet spot I described earlier, but they can be big issues at the fringes.
这是个很大的问题，因为患者控制住了血糖能预防严重的并发症，如截肢、心脏以及肾脏疾病。
That's a big problem because patients who control their blood sugar can prevent serious complications like leg amputations and heart and kidney disease.
如果在这个曲面积分中是以dx,dy,dz结尾的，则表明出现了很大的问题。
If you end up with a dx, dy, dz in the surface integral, something is seriously wrong.
这是一个很大的问题，尤其，当你年轻，因为青年和少年，是一个发现自己和自己为何物得时光？
It's a great problem. Particularly when you are young because youth and adolescence is a time of discovering yourself and what are you?
需要那么多索引的数据库的确称得上超大，这种数据库的性能和数据库管理是个很大的问题。
A database requiring an index that large is extreme and creates significant problems related to performance and database administration.
华盛顿——据新闻报道，对于许多美国青少年来说，几乎每天喝5次酒或者更多，不是一个很大的问题。
WASHINGTON - Downing five or more alcoholic drinks nearly every day is not seen as a big problem for many of the nation's teens, a new report says.
国会预算办公室的数据显示众议院提出的这项计划有一个很大的问题，就是在十年之后他的赤字会迅速增加。
The CBO figures show that this is a big problem with the House plan, whose shortfall will balloon beyond the ten-year horizon.
这些公园还要允许游客们进入，但是多大的范围，多少人以及通过什么方式进入都是争议很大的问题。
There has to be some access for visitors, but how much and for how many people and by what means remain controversial issues.
这些公园还要允许游客们进入，但是多大的范围，多少人以及通过什么方式进入都是争议很大的问题。
There has to be some access for visitors, but how much and for how many people and by what means remain controversial issues.
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