• 美国食品药品管理局已经发表异种移植指导原则草案

    America's Food and Drug Administration has already published draft guidelines for xenotransplantation.

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  • 结论完整组织原位移植提高乳腺癌异种移植成功率转移率。

    Conclusions Tumorigenicity and metastatic potential can be improved in human breast carcinoma xenografts using intact fresh tumor tissue and orthotopic grafts.

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  • 目的研究人乳腺癌异种移植的自发转移遗传稳定性微转移的检测方法。

    Objective To investigate spontaneous metastasis, micrometastasis and genetic stability in human breast carcinoma xenografts in nude mice.

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  • 研究证明药物异种移植人体肿瘤作用药物的临床疗效良好相关性

    It has been demonstrated that there exists a good correlation between the drug effect on tumor xenografts and the clinical efficacy of the drug against the correspondent tumors.

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  • 但是,一些缺乏这种监督使用材料做法未经任何质量安全控制国家开展异种移植

    However, xenotransplantation is also carried out in countries that lack such oversight and where materials and procedures used have not undergone any quality and safety controls.

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  • 免疫活性的模型缺乏小鼠细胞异种移植免疫反应表明椎间盘可能存在不为人的免疫豁免部位

    The lack of immune response to a xenograft of mouse cells in an immunocompetent rabbit model may suggest an as yet unrecognized immunoprivileged site within the intervertebral disc space.

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  • 目的临床研究表明缺损修复重建方法自体移植、异体骨异种移植、人工合成骨代用品等,其中有效、最常用的方法自体骨移植

    Objective: the Clinical study reveal that autogenous bone grafts still is the best routine methods and the best effective ways in repairing bone defect.

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  • 目的探讨同系同种胸腺异种胸腺混合移植防止器官特异性自身免疫损害可行性

    Objective to explore feasibility of prevention of organ specific autoimmune disease by transplanting mixed fetal syngeneic or allogeneic and xenogeneic thymus.

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  • 研究组织工程血管异种移植提供了可靠方法学的依据,组织工程血管的成功构建具有十分重要的意义。

    Meanwhile the research provides a potential way for heterogenic transplantation of blood vessel tissue engineering, and is also important to succeed construct tissue-engineered blood vessel.

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  • 目的(1)采用化学萃取组织工程学方法制备去细胞异种神经支架,拟异种神经移植提供理想的支架材料

    Objective (1) Take tissue engineering way of hypotonic-chemical detergent to prepare xenogeneic acellular nerve scaffold, which makes an optimal material for the graft of xenogeneic acellular nerve.

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  • 目的了解NK细胞噬细胞T细胞缺乏或T细胞成功重建的情况下异种移植排斥作用。

    Objective To evaluate the roles of natural killer (NK) cells and macrophages in the rejection of discordant xenografts in nude mice and T cell-reconstitution nude mice.

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  • 结论异种移植发生延迟排斥反应时,P选择素ICAM - 1均表达,可以作为判断异种移植免疫抑制治疗效果指标之一。

    Conclusion the expression of P-selectin and ICAM-1 in xenografts was increased during delayed xenograft rejection, which is of value in judging the effect of immunosuppression in xenotransplantation.

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  • 包膜新生猪胰岛可能将临床异种移植提供良好供体来源

    Microencapsulated neonatal pig islet would provide a fine donor source for clinical xenotransplantation of islets.

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  • 观察异种角膜上皮早期移植角膜烧伤治疗效果

    To study the treatment of rabbit with limbal alkali burn by taking early heterogenous limbal epithelium transplantation.

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  • 目的探讨血红素氧合酶- 1延迟异种心脏移植排斥反应中的表达意义

    Objective: To investigate the expression and significance of heme oxygenase-1 (HO-1) in delayed cardiac xenograft rejection in NIH-Wistar.

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  • 目的探讨异种神经脱细胞移植桥接坐骨神经缺损神经再生及其再生过程中免疫排斥反应。

    Objective To study the regeneration of the defected sciatic nerve of rat repaired by acellular heterogeneous nerve transplant and the immunoreaction after the transplant.

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  • 目的建立国外常用啮齿类动物颈部异位心脏移植标准术式,介绍金黄仓鼠大鼠异种移植中的应用

    Objectives To establish standard cervical heart transplantation in rodents that was widely used abroad and introduce its application in golden hamster rat xenotransplantation.

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  • 目的探讨异种无机复合自体骨髓移植临床应用价值。

    Objective to study the clinical application of heterogenous bone graft combined with auto - marrow.

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  • 目的综述异种移植物抗宿主反应(GVHD)动物模型研究现状检测方法进展情况

    Objective To review the current condition, test method and progress of the animal model of xenograft versus host disease (xeno GVHD).

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  • 方法体外培养血管内皮细胞不同血清共同反应建立异种移植急性排斥反应的体外实验模型

    Methods The in vitro cultured porcine vascular endothelial cells(PVEC) and human sera were co reacted to set up an in vitro model of hyperacute rejection of pig to human xenotransplantation.

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  • 目的了解异种移植物抗宿主GVHD组织学特点同种GVHD区别异种脾脏移植的关系。

    Objective To evaluate the histological characteristics of xenogeneic graft-versus-host disease(GVHD), and to differentiate it from the allogeneic GVHD.

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  • 目前没有确定证据表明异种移植安全还是危险的。

    There is no proof yet of safety or danger on cross-species infection in xenotransplantation till now.

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  • 目前应进一步加强异种器官移植基础研究

    At present time the basic research of xenogeneic transplantation should be mainly emphasized.

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  • 目的研究有效诱导异种骨髓移植耐受方法和对异基因骨髓移植重建影响

    Objective to study an effective method in inducing donor specific tolerance as well as the effects on hematopoietic reconstitution after xenogeneic-bone marrow transplantation.

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  • 霍普金斯研究小组霍普金斯医院就诊40名非转移性胰腺癌病人身上进行异种移植小鼠模型临床试验

    The Hopkins group is conducting a clinical trial of the xenograft model in 40 patients undergoing surgery at Johns Hopkins for non-metastatic pancreas cancer.

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  • 既然动物可以移植提供无尽来源,异种移植一直人们梦寐以求的事。

    Thus xenograft, or xenotransplantation is a sort of holy grail for transplantation, since animals would provide an endless supply of organs for transplantation.

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  • 探索化学萃取神经支架用于异种移植桥接面神经缺损可行性

    To explore the possibility to bridge facial nerve defects by acellular xenogeneic nerve made through chemical extraction .

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  • 结论细胞皮下移植作为研究异种移植细胞性排斥反应的模型

    Conclusion So the subcutaneous hepatocellular transplantation can be used as the model to appreciate CMXR.

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  • 目的:探讨不同方法先期处理异种神经移植神经再生影响

    To investigate the effect of pretreatment of different methods on nerve regeneration after heterografting.

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  • 目的研制带密集异种无细胞真皮替代物提高真皮替代物自体皮复合移植的存活率。

    Objective To prepare acellular xeno dermal substitute with micropores in order to promote engraftment rate of autologous skin combined with dermal substitute.

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