目的：合成头孢克肟侧链活性酯。
Objective: To study the synthetic technique of cefixime activated thioester.
目的：研究头孢克肟口含片的处方工艺。
Objective: To study the formulation and procedure of cefixime buccal tablets.
目的粉末直接压片法研究制备头孢克肟片。
OBJECTIVE Study on preparing cefixime tablets with direct compression method.
目的：对市售头孢克肟分散片和胶囊进行溶出度比较。
Objective: To compare the dissolution of the dispersible tablet and the capsule of cefixime.
结论：该方法简便可靠，可用于头孢克肟口含片的质量控制。
Conclusion: the methods is reliable and accurate, it can be used for quality control the cefixime buccal tablets.
目的探讨头孢克肟和头孢克洛治疗小儿呼吸道感染的临床疗效。
Objective To investigate the clinical efficacy of cefixime and cefaclor in the treatment of respiratory tract infection in children.
目的：观察口服头孢克肟联合三金片治疗尿路感染的临床疗效。
Objective To observe the clinical effect of oral cefixime in combination with Sanjin tablets on urinary tract infection.
头孢克肟抗菌谱广、半衰期长、交叉耐药性小、用药剂量小、适应症广泛。
Cefixime is characterized by broad spectrum, long half life period, less cross resistance to chemical reagent, small use dosage and wide scope of application.
以乙酰乙酸叔丁酯为原料，经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
通过本发明方法制备的头孢克肟酸式复盐纯度、含量高，具有稳定性好、不易产生聚合物等特点。
The cefixime acid type double salt prepared by the method has the characteristics of high purity and content, good stability, difficult generation of polymers and the like.
方法用紫外分光光度法和释放度试验，考察头孢克肟缓释片在不同释放介质中不同释放时间的累积释放度。
Methods Ultraviolet spectrophotometry and release test were applied to determine the release of cefixime in cefixime sustained-release tablets under different media and time points.
结果表明，该法能有效检测头孢克肟的中间体，具有柱效高、经济等优点，可用于头孢克肟反应过程的监测。
The results show that the method can detect the content of cefixime intermediates effectively and economically. This HPLC method can be used to monitor the cefixime reaction process.
方法用中国医科大学附属第一医院承担的头孢克肟生物等效性试验作为范例分析，计算了传统生物等效性检验和数理相似性检验。
METHODS the bioequivalence test of cefixime done by the first affiliated of China Medical University was analyzed by the traditional method and statistics similarity method.
方法用中国医科大学附属第一医院承担的头孢克肟生物等效性试验作为范例分析，计算了传统生物等效性检验和数理相似性检验。
METHODS the bioequivalence test of cefixime done by the first affiliated of China Medical University was analyzed by the traditional method and statistics similarity method.
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