研究人员发现了一些人已经发生了极少量的基因变异,这种变异减少了细胞对某种生长激素(即,胰岛素样生长因子1(IGF1))的使用。
Researchers have discovered that some people have a rare genetic mutation that decreases their cells' use of a particular growth hormone: insulin-like growth factor 1 (IGF1).
表皮生长因子受体通常促进细胞的生长发育,一旦发生基因变异,会使细胞不受控制地生长。细胞不受控制地生长,这正是癌症的特征。
EGFR normally promotes cell growth and development, and when mutated, allows the uncontrolled growth of cells that is the hallmark of cancer.
非小细胞肺癌病人的表皮生长因子受体基因突变的临床病理意义。
Clinicopathologic Significance of the Mutations of the Epidermal Growth Factor Receptor Gene in Patients with Non-Small Cell Lung Cancer.
BFGF细胞生长因子经高科技基因生物工程提炼而成。
The BFGF cell growth factor becomes after the high tech gene bio-engineering refinement.
十多年前就取得了重大进展,一个加州的生物科技公司Genentech(中文名:基因泰克)发行了一种药物,这种药物攻击蛋白质HER2(中文名:人表皮生长因子受体- 2)含量过多的乳腺癌细胞。
A breakthrough came more than a decade ago when Genentech, a Californian biotech firm, launched a drug that attacks breast-cancer cells with too much of a certain protein, HER2.
转录最高的基因与功能相关,如细胞粘附,基质蛋白,生长因子,受体和蛋白酶。
The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.
目的观察脑溢安血清对体外缺氧培养的大鼠脑微血管内皮细胞血管内皮生长因子(VEGF)基因表达的影响。
Objective To study the effects of Nao Yi An(NYA) serum on the expression of vascular endothelial growth factor(VEGF) gene in cultured rat cerebral microvascular endothelial cell(BMEC)with hypoxia.
目的探讨醛固酮对大鼠肾小球系膜细胞结缔组织生长因子基因表达的影响。
To evaluate the effect of aldosterone on connective tissue growth factor mRNA expression in cultured rat mesangial cells.
这是FDA批准的首个能够检测非小细胞肺癌患者表皮生长因子受体(EGFR)基因突变的、以血液为基础的基因检测试剂盒。
This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.
实验通过原位分子杂交技术,检测人骨髓巨核细胞分化发育过程中神经生长因子( NGF)基因表达情况。
The expression of nerve growth factor (NGF) gene during development of megalocaryocytes was studied by in situ hybridization.
科学家发现,当细胞首次接收到生长因子的信号时,有10组共8000个基因被激活。
The scientists found that when a cell first receives a signal from a growth factor, ten groups of genes, about 8,000 in total, become activated.
目的探讨成纤维细胞生长因子1(FGF-1)基因启动子多态性是否与晚发型阿尔茨海默病(LOAD)相关。
ObjectiveTo evaluate the correlation between the promoter polymorphism of Fibroblast Growth Factor 1 (FGF-1) and late-onset Alzheimer's disease (LOAD).
本文对垂体腺瘤中基因突变、转录因子、细胞表达受体、生长因子的作用及关系作一述评。
This paper reviews the roles of gene mutations, transforming factors, expression of receptors on cells and growth factors in the etiology of pituitary adenomas.
目的研究生长抑素类似物奥曲肽(oct)对体外培养的大鼠肝星状细胞(HSC)中结缔组织生长因子(CTGF)基因表达的影响。
ObjectiveTo investigate the effect of somatostatin analogue-octreotide (oct) on expression of connective tissue growth factor (CTGF) gene of murine hepatic stellate cells (HSCs) in vitro.
目的研究胰岛素样生长因子i受体(IGFIR)基因表达对脐血t淋巴细胞功能的影响及其临床意义。
Objective to study the role of insulin like growth factor type I receptors (IGF IR) in the modulation of cord blood t lymphocyte functions and its clinical significance.
目的对人工合成的人广谱细胞生长因子基因进行体外表达与纯化,并测定其活性。
Objective to express the basic fibroblast growth factor (bFGF) gene in bacteria, to purify the product and to determine its activity.
目的克隆人表皮生长因子受体(HER2)基因,建立共表达HER2基因和雌激素受体(ER)基因的MCF-7细胞模型。
Objective To clone human epidermal growth factor receptor (HER2) gene and establish a MCF-7 cell line with stable co-expression of HER2 and estrogen receptor (ER).
目的探讨胰腺癌细胞(PC-3)胰岛素样生长因子-1受体(IGF- 1R)基因的定量表达,及其与细胞凋亡、成瘤性的关系。
Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.
目的探讨转染表皮细胞生长因子(EGF)基因的人表皮细胞移植后egf的表达及对细胞增殖的影响。
Objective to investigate the epithelial growth factor (EGF) expression of EGF gene-transfected keratinocytes and its effect on cell proliferation after grafting.
目的:探讨血管内皮细胞生长因子(VEGF)基因多态与血浆VEGF浓度以及脑卒中患病风险的关系。
Objective: to assess the gene polymorphisms and concentration of vascular endothelial growth factor (VEGF) and the risk for stoke.
目的探讨CT导引下肝细胞生长因子(HGF)基因治疗脑缺血的可行性。
Objectives To investigate the feasibility of CT guided hepatocyte growth factor(HGF)gene therapy for cerebral ischemic diseases.
目的探讨中国人非小细胞肺癌表皮生长因子受体(EGFR)第18、19、21外显子基因突变状态。
Objective to study the mutation patterns of epithelial growth factor receptor (EGFR) exon 18, 19 and 21 in Chinese non-small-cell lung cancers (NSCLC).
探讨利用基因枪技术转移肝细胞生长因子基因治疗大鼠肢体闭塞性血管病的可行性。
To explore the feasibility of gene therapy with hepatocyte growth factor (HGF) transferred using gene gun technique in treatment of peripheral vascular disease of rat limb.
目的研究超声微泡促进TDL复合物介导的肝细胞生长因子(HGF)基因在人脐静脉内皮细胞(HUVEC)中的转染效果。
Objective To study the transfection effects of ultrasound microbubbles enhanced TDL compound mediated HGF gene in human umbilical vein endothelial cell (HUVEC).
在调控基因中,大多是众多的生长因子基因和影响细胞粘附、细胞信号转导及细胞周期调控或者其它功能的基因。
Among the regulated genes are numerous growth-factor genes and genes affecting cell adhesion, cell signaling, cell-cycle regulation, and other functions.
探讨重组2型腺相关病毒载体介导2型成纤维细胞生长因子基因诱导家兔缺血心肌血管生成的作用。
Aim To investigate the effect of fibroblast growth factor 2 (FGF2) cDNA mediated by recombinant adeno-associated viral vector2 (rAAV-2) on ischemic myocardium.
目的通过观察激素治疗兔关节炎模型过程中滑膜组织内血管内皮细胞生长因子(VEGF)的基因表达,进一步探讨激素治疗关节炎的作用机制。
Objective to observe the expression of vascular endothelial growth factor (VEGF) in synovial tissue during treatment of rabbit arthritis model with corticosteroids and explore its mechanism.
目前认为垂体腺瘤的发生与基因突变、生长因子、细胞受体、转录因子和细胞信号通路等有关。
The pathogenesis of pituitary adenomas is considered to be related with gene mutation, growth factors, cell receptors, transcription factors, and cellular signaling pathways.
目的:探讨表皮生长因子受体(EGFR)基因酪氨酸激酶域体细胞在肺腺癌患者中突变的相关因素。
Objective: to study Somatic mutation of the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR gene) in lung adenocarcinoma patients.
结论:血管内皮生长因子基因转染可促进骨髓基质细胞的成骨分化。
CONCLUSION: Transfection with VEGF 165 gene can promote the osteogenic differentiation of cultured MSCs.
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