其功能与周期蛋白和周期蛋白依赖性激酶形成的异源三聚体存在化学计量关系。
It functions in stoichiometric relationships forming heterotrimeric complexes with cycling and cyclin-dependent kinases.
免疫细胞化学法检测细胞周期蛋白及凋亡相关基因蛋白的表达。
The expression of cell cycle protein and apoptosis-associated gene protein was detected with immunohistochemical technique.
免疫细胞化学法检测细胞周期蛋白及凋亡相关基因蛋白的表达。
The expression of cell cycle protein and apoptosis-associated genes protein was detected with immunohistochemical technique.
当在临床实验中第一次检测到细胞周期蛋白时，对人体是有害的。
When it was initially tested in clinical trials, it was found to be toxic in humans.
在植物中a型和B型细胞周期蛋白依赖性激酶直接参与调控细胞周期。
In plants, a - and B-type CDKs are directly involved in cell cycle regulation.
目的深入研究周期蛋白d 1在鼻咽癌细胞中的表达特征及其生物学功能。
Objective in the present study, we tried to further elucidate the expression and function of cyclin D1 in human nasopharyngeal carcinoma (NPC) cell line.
目的探讨经载体介导的RNA干扰对肝癌细胞周期蛋白E1表达抑制效率。
Objective To explore the inhibition of expression of cyclin E1 in hepatocellular carcinoma via RNA interference mediated by siRNA expressing vector.
结论载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白d1的表达和激活。
Conclusion Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line.
结论缬沙坦可能通过影响细胞周期蛋白p 27表达而抑制肾脏肥大，从而发挥肾脏保护作用。
Conclusion the protective effect of valsartan on diabetic kidney may be partly through inhibiting renal hypertrophy by regulating the expression of cell cycle related protein P27.
生长因子退出后，通过下调蛋白表达和磷酸化依赖性蛋白降解，周期蛋白D的水平下降（4）。
Levels of cyclin D protein drop upon withdrawal of growth factors through downregulation of its protein expression and through phosphorylation-dependent degradation (4).
我们确定了几个类型在水稻基因组的细胞周期蛋白基因和特征的系统发育，串联重复片段的分析。
We identified several types of cyclin genes in the rice genome and characterized them by phylogenetic, tandem and segmental duplications analyses.
这两个克隆都包含有一段DNA序列，能在在细胞周期蛋白d1的RNA被转录的时候将荧光蛋白绑定到其上。
Both clones included a DNA sequence that allow a fluorescent protein expressed in the cell to bind to cyclin D1 RNA the moment it is transcribed.
本文将从细胞周期的调控，细胞周期蛋白d1的发病机制及其与口腔扁平苔藓癌变的联系简要综述。
We reviewed researches on the regulations of cell cycle, the pathogenesis of CyclinD1, and their association with the cancerization of OLP.
目的：探讨胃癌RUNX3蛋白表达对细胞周期蛋白的影响及其与胃癌患者生存和生物学特性的关系。
AIM: To evaluate the relationship between RUNX3, cyclin e, P21, biological features and survival in gastric cancer patients.
目的：探讨苯那普利对糖尿病大鼠肾组织细胞周期蛋白激酶抑制剂p 21 CIP1蛋白表达的影响。
To investigate the effect of benazepril on expression of cyclin kinase inhibitor P21 CIP1 protein in renal tissue of diabetic rats.
目的观察细胞周期蛋白依赖性激酶- 2 (CDK - 2)在SH -SY5Y细胞中的表达情况。
Objective To investigate the expression of cyclin-dependent kinase-2 (CDK-2) gene in SH-SY5Y cells.
口腔扁平苔藓(olp)是最常见的口腔黏膜病之一，其癌变趋势与细胞周期蛋白d1有着极其密切的关系。
The oral lichen planus is one of the most common disease of oral mucosa. The relationship between the trend of cancerization in OLP and the expression of CyclinD1 is extremely close.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达，了解其在翼状胬肉发病机制中的作用。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
细胞周期蛋白d1在癌症中经常过表达，可引起其过表达的因素很多，包括增加转录，翻译和蛋白质的稳定性。
Cyclin D1 is frequently over-expressed in cancers and its overexpression can be attributed to many factors including increased transcription, translation, and protein stability.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
结论翼状胬肉中细胞周期蛋白依赖性激酶抑制剂p16的低表达可能导致翼状胬肉细胞周期紊乱，其增殖失去控制。
Conclusion The lower expression of cell circle related kinase inhibitor in pterygium may play an important role on proliferation and pathogenesis of pterygium.
细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶（CDK）复合物来调控。
Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.
采用体外诱导卵母细胞成熟技术，比较研究了雌核发育银鲫和两性融合发育彩鲫卵母细胞成熟过程中周期蛋白合成和MPF活性变化情况。
The changes in cyclin synthesis and MPF activity during oocyte maturation in vitro in gynogenetic silver crucian carp and amphimictic colored crucian carp were compared.
他们发现，由一个分子对另外一个EGFR激酶结构域的不对称激活类似于涉及调控细胞生长的细胞周期蛋白激活细胞周期蛋白依赖型激酶的方式。
They found that the asymmetric activation of one EGFR kinase domain by another is analogous to the activation of cyclin-dependent kinase (CDK) by cyclin, which are involved in regulating cell growth.
我们的 结果表明，有至少49个预测的水稻细胞周期蛋白基因在水稻基因组，它们被分布在 12条染色体。
Our results indicated that there were at least 49 predicted rice cyclin genes in the rice genome, and they were distributed on 12 chromosomes.
cdc2蛋白激酶的激活参与调节真核细胞进入有丝分裂，cdc2的激活受多个步骤的调控，包括周期蛋白的结合、cdc2苏氨酸161位的磷酸化(1)。
The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161 (1).
因为老鼠在出生时没有髓磷脂损害，我们假设这种蛋白是为了维持髓磷脂的质量，并且在整个生命周期内会逐渐减小。
"Because there is no myelin damage at birth, we assumed prions are needed to maintain the quality of the myelin sheath, which diminishes throughout life," says Aguzzi.
蛋白酶是一种蛋白质，对于引发AIDS的HIV病毒的生命周期至关重要。
Protease is a protein crucial to the life cycle of HIV, the AIDS-causing virus.
然后他们检查生物指标——叫做抗氧化蛋白的蛋白质——经历24小时的周期。
They then examined the levels of biochemical markers – proteins called peroxiredoxins – that are produced in high levels in blood and found that they underwent a 24-hour cycle.
科学家发现一种名为增食欲素(orexin)的蛋白质与调节睡眠周期有关。
The scientists also found a link with orexin, a protein involved in regulating the sleep cycle.
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