阳离子脂质体能促进AS - ODN的反义抑制作用。
Cationic liposome can enhance AS ODN antisense inhibitory effect.
目的：研究细胞间粘附分子- 1 (ICAM - 1)反义dna对内皮细胞ICAM - 1表达的抑制作用。
Objective: to observe inhibitory effect of intercellular adhesion molecule1 (ICAM1) antisense DNA on ICAM1 expression in endothelial cells.
目的：利用纳米载体增强端粒酶反义寡核苷酸对肝脏肿瘤细胞生长的抑制作用。
Objective: To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by albumin nanoparticles.
【摘要】目的探讨增殖细胞核抗原(pcna)反义寡核苷酸对大鼠胶质瘤生长的抑制作用。
Abstract Objective to study the inhibitory effect of PCNA antisense oligonucleotides on the growth of rat glioma.
结果VEGF反义寡核苷酸对膀胱癌细胞的VEGF表达有明显的抑制作用。
Results VEGF antisense oligonucleotides obviously inhibited VEGF expression in human bladder carcinoma cells and proliferation of endothelial cells.
通过TGEV分别感染IBRS2和IBRS2抗性细胞产生的病变，结果表明该反义RNA对病毒的复制有抑制作用，其抑制率近50%。
Antiviral activitity of the antisense RNA was evaluated by cytopathic effect using cultured IBRS2 cell and anti- IBRS2 cell infected by TGEV respectively, and the inhibitory rate was about 50%.
由于人体细胞的无义突变也可能敏感于反义试剂的抑制作用，这就为治疗由于无义突变导致的多种疾病提供了一个新途径。
Nonsense termination in human cells may also be susceptible to suppression by antisense agents, providing a new approach to address numerous diseases caused by nonsense mutations.
目的研究角质形成细胞生长因子(KGF)及其受体(KGFR)反义寡核苷酸对KGF介导的细胞周期和凋亡变化的抑制作用。
Objective to investigate the effects of keratinocyte growth factor (KGF) and KGF receptor (KGFR) antisense oligonucleotide (ASODN) on cell cycle and apoptosis of HaCat cells.
方法在小鼠角膜肿瘤模型上，测定两种VEGF反义核酸序列的5种不同修饰之反义核酸，对肿瘤血管形成和肿瘤生长的抑制作用。
Methods with a tumor model on the cornea of rat the inhibition of angiogenesis and tumor growth by 5 ODNs with different modifications and sequences was determined.
结论pcna基因反义rna对胃癌细胞的生长具有明显的抑制作用。
Conclusion PCNA antisense RNA can significantly suppress the in vitro growth of gastric cancer cell line.
目的研究内皮素转换酶-1（ECE -1）反义RNA对人气道上皮细胞ECE -1表达的抑制作用。
Objective To explore the effects of endothelin converting enzyme-1 (ECE-1) antisense RNA on ECE-1 expression in human bronchial epithelial cell line(16HBE).
研究Bcl - 2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.
研究Bcl - 2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.
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